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First Trimester Screen (087-3750, 087-3753)
Test Mnemonic:


Specimen Requirements:
Test Included:

Beta hCG, PAPP-A


7mL of blood in SST or red stop tube. (Min.: 3mL of blood).

Minimum Volume:

3 mL of blood


Deliver to Sample Management within 2 hours of collection.

Specimen Preparation:

Allow specimen to clot completely at room temperature. Centrifuge to separate serum from cells within 2 hours of collection. Transfer serum from collection tube to labeled plastic transport tube. 


Room temperature for ≤ 8 hours, refrigerated for ≤ 24 hours or frozen at -20°C or colder. (Avoid repeated freeze/thaw cycles).

Causes for Rejection:

Patient is less than or greater than the gestational age cutoff, incomplete and/or incorrect sample identification, improper storage/transport , and gross hemolysis or lipemia.

Reference Range:

By report (reports may vary based on instrumentation, patient age and sex)

Turnaround Time:

M-F: within 24 hours




Monday – Friday: 7 am – 3:30 pm     


Special Chemistry

Clinical Indication:

Screening Test for Down Syndrome and Trisomy 18 risks in pregnant women

Patient Preparation :


Patient must be in the First Trimester between 10 weeks, 0 days and 13 weeks, 6 days

CPT 4 Code:

84702, 84163


Please provide completed patient information sheet with sample.  Not available on Week-ends.

When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent.
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