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Cryoprecipitate (10006422)
Test Mnemonic:


Specimen Requirements:


Volume:  minimum 3 mL (if Type and Screen is needed)

Test Included:

A Type and Screen must be performed during this hospital admission and  prior to transfusion.  (A physician's waiver permits emergency release of blood products prior to completion of testing but does not eliminate the requirement for testing to occur.)   Depending on the patient condition, a fibrinogen level or other hematology testing may also be required. 


Cryo:  Keep at room temperature; do not refrigerate.

Type and Screen:  Samples are accepted 24 hours per day at the Blood Bank lab, 4.404 Clinical Services Wing (CSW).  All requests must include requesting physician’s name and ID number, patient's name, UH #, patient location, clinical information/diagnosis, phlebotomist and verifier's name and collection date and time.  Request form must be filled out completely and all information must be legible.


CRYO thawed for transfusion expires in 4 to 6 hours, depending on the method of preparation.

Causes for Rejection:

Requests may be denied if Transfusion Guidelines are not met;  the blood bank physicians are available for telephone consultation regarding the type or quantity of blood components recommended to treat a patient.

Reference Range:
Turnaround Time:

1 hour


CRYO for transfusion can be ordered 24 hours per day from the Blood Bank lab, 4.404 Clinical Services Wing (CSW). 


AHF, Antihemophilic Factor, Antihemophilic Globulin, Cryo

Clinical Indication:

Refer to the UTMB Guidelines for Transfusion of Blood and Blood Components (also known as Transfusion Criteria);  a link can be found on the homepage of the Laboratory Survival Guide.

An adult dose is usually 5 units and may be supplied as a pool of 5 units.

Documentation of clinical and laboratory response to transfusion of CRYO is recommended within 1 hour after the transfusion is complete.

CPT 4 Code:



All blood components, including Cryoprecipitate, are dispensed from the Blood Bank lab, 4.404 Clinical Services Wing (CSW).

When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent.
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