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IgG Antibody Titration, Immune (10005509)
Test Mnemonic:


Specimen Requirements:
Test Included:

Serial titration of antibody reactivity following IAT testing and antibody identification studies in prenatal patients.


Routine venipuncture


Lavender-top tube (EDTA)

Minimum Volume:



Ambient temperature

Causes for Rejection:

Specimen improperly labeled, requisition incomplete, serum separator tube used, gross hemolysis, frozen sample, failure to identify phlebotomist and verifier

Reference Range:

Not applicable

Turnaround Time:

2 days


Serial saline titration and testing by hemagglutination


Specimens are accepted 24 hours per day at the Blood Bank lab, 4.404 Clinical Services Wing (CSW).


Antibody Titer, Prenatal Titer, IgG Titer

Clinical Indication:

Used primarily to track the relative strength of clinically significant red-cell stimulated antibodies in prenatal patients where the antibody may impact the health of the fetus and may present difficulties in compatibility testing for mother and newborn at the time of delivery.   Antibody titration studies may be done occasionally for other patient populations and clinical situations.

CPT 4 Code:



All requests must include the requesting physician's name and ID number, patient's complete name, UH number, current account number, patient location, clinical diagnosis, identity of phlebotomist and verifier, and the date/time of sample collection.  The specimen must be labeled with the patient's full name and UH number.  Specimens should be transported to the laboratory in a biohazard specimen bag with the request form in the pocket of the bag.  All information must be complete and legible on the specimen and the requisition.

When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent.
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