| Protein C Functional (LAB001562) | |
|---|---|
| Test Mnemonic: | PROTEIN C |
| Specimen Requirements: | |
| Collection: | Blue-topped (3.2% sodium-citrate) tube. Routine venipuncture; discard 1st ml of blood by collecting a discard tube prior to collecting the blue-topped (3.2% sodium-citrate) tube. For collections with butterfly blood collection sets, a discard tube should also be collected prior to collection of the blue top to ensure sufficient sample volume. Drawing a discard tube will displace the air from the blood collection set tubing to ensure proper blood draw volume. |
| Container: | Blue-topped (3.2% sodium-citrate) tube. |
| Minimum Volume: | 2 ml of plasma. |
| Storage/Transport: | Critically frozen. |
| Specimen Preparation: | Separate cells within 2 hours of collection as follow: centrifuge the specimen for 15 minutes at 2000-2500g. Transfer the plasma to a 12x75 plastic tube, cap the tube and centrifuge it again for 15 minutes at 2000-2500g. Carefully remove from centrifuge without disturbing any platelets and / or cell pellets that might be on the bottom or sides of the tube. Carefully transfer plasma into freezer tubes (plastic screw-top cryo-tubes) and freeze plasma. Avoid freeze/thaw cycles.
|
| Stability: | 3 months ≤-20 °C; 6 months ≤-70 °C. |
| Causes for Rejection: | Serum, EDTA plasma, QNS, clotted, severely hemolyzed specimen, wrong tube, high hematocrit (> 55%), sample identification error, sample processed/transported, and/or stored improperly. |
| Reference Range: | 70-140% |
| Turnaround Time: | 4 days |
| Methodology: | Chromogenic. |
| Performed: | Once a week on Fridays. |
| Lab: | Antiphospholid Standardization Laboratory CLIA 45D107321 |
| Synonyms: | PROT C FUNCTIONAL, PROTEIN C ACTIVITY, PROT C ACTIVITY |
| CPT 4 Code: | 85303 |
| When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient. Components of the organ or disease panels may be ordered individually. The diagnostic information must substantiate all tests ordered and must be in the form of an ICD-10 code or its verbal equivalent. | |