UTMB MD-PhD Program Current Students Profile Brian Dawes Brian DawesYear in Program: MY4Undergrad University: University of Illinois at UrbanaMentor: Alex Freiberg, PhDGraduate Program: Microbiology and Immunology Brian Dawes Research Interests Molecular pathogenesis of emerging viruses and vaccine development Honors and Awards Jeane B. Kempner Scholarship (2017) GSBS Associates Endowment (2016) T32 Trainee, NIAID 2T32AI007526 “Emerging and Tropical Infectious Diseases” (2016-present) Blocker Scholar Fellowship (2014) Harvey L. Pretula Memorial Undergraduate Research Award (2011) Molecular and Cellular Biology Honors Program (2009) Edmund J. James Scholar (2008) College of Liberal Arts and Sciences Dean's List Publications Bharaj P, Atkins C, Luthra P, Giraldo MI, Dawes BE, Miorin L, Johnson JR, Krogan NJ, Basler CF, Freiberg AN, Rajsbaum R. The host E3-Ubiquitin ligase TRIM6 ubiquitinates the Ebola virus VP35 protein and promotes virus replication. J Virol. 2017 Jul 5. pii: JVI.00833-17. doi: 10.1128/JVI.00833-17. Bharaj P, Wang YE, Dawes BE, Yun TE, Park A, Yen B, Basler CF, Freiberg AN, Lee B, Rajsbaum R. The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response. PLoS pathogens. 2016; 12(9):e1005880. Dawes B, Smalley C, Tiner B, Beasley D, Milligan G, Reece L, Hombach J, Barrett A. Research and development of Zika virus vaccines. NPJ Vaccines. 2016 July 28; 1:16007. Park A, Yun T, Vigant F, Pernet O, Won ST, Dawes BE, Bartkowski W, Freiberg AN, Lee B. Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway. PLoS Pathog. 2016. 12(5):e1005659 Satterfield BA, Dawes BE, Milligan GN. Status of vaccine research and development of vaccines for Nipah virus. Vaccine. 2016. 34(26): 2971-5 Presentations Dawes B., Gao J., Wu P., Freiberg A., Infection of Human Neuronal Stem Cell Derived Neuron/Astrocyte Co-Cultures with La Crosse Virus. Oral presentation at the 34th Annual Meeting of the American Society of Virology; 2015 Jul 11-15; London, ON, Canada Dawes B., Zhang L., Komeno T., Furuta Y., Freiberg A., T-705 (favipiravir) activity against Henipaviruses. Oral presentation at the 34th Annual Meeting of the American Society of Virology; 2015 Jul 11-15; London, ON, Canada Dawes B., Gao J., Wu P., Freiberg A., Infection of Human Neuronal Stem Cell Derived Neuron/Astrocyte Co-Cultures with Henipaviruses. Oral presentation at the 35th Annual Meeting of the American Society of Virology; 2016 Jun 18-23; Blacksburg, VA, United States of America Dawes B., Gao J., Wu P., Freiberg A., Responses of Human Neuronal Cells to Nipah Virus Infection. Poster presentation at the Cell Symposia: Emerging and Re-emerging Viruses, Oct 2017, Arlington, VA