|Maria D.H. Alcorn
My research will focus on determining the mechanism and functions of nonstructural protein 1 of coronaviruses.
I am interested in ticks and tickborne diseases, specifically tick borne encephalitis and spotted fever group Rickettsia infections. I am working in Dr. Walker's laboratory studying tick transmission of Rickettsia massiliae and the early immune events following infection.
|Andrew S. Beck
Pathogenesis of yellow fever disease, determinants of attenuation for the yellow fever vaccine strain 17D-204
|Nicholas A. Bergren
My primary area of research interest is geared towards developing novel, safe, and efficacious vaccine candidates for emerging infectious diseases primarily by way of genetic modification of the virus. I also am interested in studying mechanisms of virulence and attenuation in vitro and in vivo, and would ultimately like to elucidate genetic determinants of virulence. A comprehensive understanding of viral genetics will allow the scientific community to better understand pathogenic mechanisms and as a result develop more effective vaccines and therapeutics.
My research will focus on the role of neutrophil in the pathogenesis of inflammatory bowel disease (IBD) and how neutrophil interact with microbiota.
My research will focus on genetic determinants of pathogenesis for hemorrhagic arenaviruses, with a focus on live attenuated vaccine development.
|Meghan E. Hermance
My research will focus on the tick-borne flavivirus, Deer tick virus (DTV), and its natural vector, Ixodes scapularis. The long term goal of my research is to study the early host immune response to tick-borne flaviviruses. I will additionally investigate how I. scapularis endosymbionts influence the vector competence of DTV.
I am interested in novel immune cell signaling pathways that regulate inflammation during infection with pathogens. My research will focus on the metabolism of macrophages that enhance the pro-inflammatory capacity to clear the etiologic agent of Chagas cardiomyopathy, Trypanosoma cruzi.
|Hoai J. (Jaclyn) Ly
I am interested in Rift Valley Fever Virus MP-12 Vaccine with Silent Mutation Markers for Reassortment and Recombination Analyses between RVFV Strains and other bunyaviruses.
|John T. Manning
My goal is to investigate different attenuating factors within the genomes of New World arenaviruses in order to develop attenuated live vaccine candidates.
|Sandra V. Mayer
My research interest is to study dengue pathogenesis in a humanized mouse model.
My research interest is cellular microbiology.
My research interest is genetic analysis and vaccine development for flaviviruses.
I started my Ph.D. study on Rift Valley fever virus (RVFV) in particular for the vaccine development. The overall aim of my Ph.D. study is to develop highly safe candidate vaccine which specifically target DC, and the spread is restricted after infection.
My research lab focuses on neurological sequelae resultant alphavirus and arenavirus infections.
|Adam J. Ronk
My research focuses on filovirus replication and transcription. Effects of the innate immune response and viral interferon antagonism on filovirus polymerase function. Comparative immunology of pteropoid fruit bats in the context of filovirus infection.
I am interested in Rickettsia spp and host endothelial cell interactions. I am examining Rickettsia spp use of type IV secretion systems.
|Jesus A. Silvas
My main interest lies in understanding the molecular pathogenesis of emerging viral diseases. Currently, my research is focused on understanding how a novel virus, Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV), counteracts the innate immune response.
My research will focus on protective innate immune mechanisms of the host in response to rickettsial infection.
My research will focus on Immune response to Orientia tsutsugamushi.
I study infectious diseases like Rickettsia and Dengue. I not only comprehensively inspect the pathogens, but also investigate the response of host immunity.
Jere W. McBride, Ph.D.
Professor, Department of Pathology
Center for Biodefense and Emerging Infectious Diseases
Sealy Center for Vaccine Development
Director, Experimental Pathology Graduate Program
Office: (409) 747-2498
Fax: (409) 747-2455