Robert B. Tesh, M.D.

Robert B. Tesh, M.D.

Professor, Departments of Pathology, Microbiology and Immunology, Preventive Medicine and Community Health;
Center for Biodefense and Emerging Infectious Diseases;
Sealy Center for Vaccine Development;
Institute for Human Infections and Immunity

University of Texas Medical Branch
301 University Boulevard
Galveston, TX 77555-0609

Office: (409) 747-2431
Fax: (409) 747-2429

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Robert B. Tesh, M.D.

Professional Education

Degree Institution Field of Study Graduation Year
B.S. Franklin and Marshall College, Lancaster, PA Zoology 1957
M.D. Jefferson Medical College, Philadelphia, PA M.D. 1961
M.S. Tulane University, New Orleans, LA Epidemiology 1967
Intern San Francisco General Hospital, San Francisco, CA Intern 1962
Resident Gorgas Hospital, Balboa Heights, CZ, Panama Pediatrics 1963
NIH Post-Doctoral Fellow Tulane University School of Medicine, New Orleans, LA Pediatric Infectious Diseases 1967


  • Fellow, American Association for the Advancement of Science
  • 2002 Researcher of the Year, Department of Pathology, UTMB

Professional Affiliations

  • American Association for the Advancement of Science
  • American Society for Microbiology
  • American Society for Tropical Medicine and Hygiene
  • American Committee on Arthropod-borne Viruses
  • Entomologic Society of America
  • American Mosquito Control Association
  • Society of Vector Ecology

Research Interests

Epidemiology, pathogenesis and natural history of arthropod-borne and zoonotic viral diseases; isolation and characterization of novel vertebrate and arthropod viruses.

Selected Publications

  1. Aitken THG, TESH RB, Beaty BJ, Rosen L: Trans-ovarial transmission of yellow fever virus by mosquitoes (Aedes aegypti). Am J Trop Med Hyg 28: 119-121, 1979.
  2. Ribeiro JMC, Vachereau A, Modi GB, TESH RB: A novel peptide from the salivary glands of the sand fly Lutzomyia longipalpis is a potent vasodilator. Science 243: 212-21-4, 1989.
  3. Walters LL, Modi GB, Chaplin GL, TESH RB: Ultrastructural development of Leishmania chagasi in its vector, Lutzomyia longipalpis (Diptera: Psychodidae). Am J Trop Med Hyg 41: 295-317, 1989.
  4. Chen WR, TESH RB, Rico‑Hesse R: Genetic variation of Japanese encephalitis virus in nature. J Gen Virol 71: 2915-2922, 1990.
  5. TESH RB, Lubroth J, Guzman H: Simulation of arbovirus over wintering: survival of Toscana virus (Bunyaviridae: Phlebovirus) in its natural sand fly vector, Phlebotomus perniciosus. Am J Trop Med Hyg 47: 574-581, 1992.
  6. TESH RB, Jahrling PB, Salas RA, Shope RE: Description of Guanarito virus (Arenaviridae: Arenavirus), the etiologic agent of Venezuelan hemorrhagic fever. Am J Trop Med Hyg 50: 452-459, 1994.
  7. Manzione N de, Salas RA, Paredes H, Godoy O, Rojas L, Araoz F, Fulhorst CF, Ksiazek TG, Mills JN, Ellis BA, Peters CJ, TESH RB: Venezuelan hemorrhagic fever: clinical and epidemiologic studies of 165 cases. Clin Infect Dis 26: 308-313, 1998.
  8. TESH RB, Watts DM, Russell K, Damodaran C, Calampa C, Cabezas C, Ramirez G, Vasquez B, Hayes CG, Rossi CA, Powers AM, Hice CL, Chandler LJ, Cropp BC, Karabatsos N, Roehrig JT, Gubler DJ. Mayaro virus disease: an emerging mosquito-borne zoonosis in tropical South America. Clin Infect Dis 28: 67-73, 1999.
  9. Fulhorst CF, Ksiazek TG, Peters CJ, TESH RB. Experimental infection of the cane mouse Zygodontomys brevicauda (family Muridae) with Guanarito virus (Arenaviridae), the etiologic agent of Venezuelan hemorrhagic fever. J Infect Dis 180: 966-969, 1999.
  10. TESH RB, Guzman H, Travassos da Rosa APA, Vasconcelos PFC, Dias LB, Bunnell JE, Zhang H, Xiao S-Y. Experimental yellow fever virus infection in the golden hamster (Mesocricetus auratus). 1. Virologic, biochemical and immunologic studies. J Infect Dis 183:1431-1436, 2001.
  11. Xiao S-Y, Zhang H, Guzman H, TESH RB. Experimental yellow fever virus infection in the golden hamster (Mesocricetus auratus). 2. Pathology. J Infect Dis 183:1437-1444, 2001.
  12. Xiao S-Y, Guzman H, Zhang H, Travassos da Rosa APA, TESH RB. West Nile virus infection in the golden hamster (Mesocricetus auratus): a model of West Nile encephalitis. Emerg Infect Dis 7:714-721, 2001.
  13. Ratterree MS, Gutierrez RA, Travassos da Rosa APA, Dille JB, Beasley DW, Bohm RP, Desai SM, Didier PJ, Bikenmeyer LG, Dawson GJ, Leary TP, Schochetmann G, Phillippi-Falkenstein, Arroyo J, Barrett ADT, Tesh RB. Experimental infection of rhesus monkeys with West Nile virus: level and duration of viremia and kinetics of the antibody response. J Infect Dis 189: 669-676, 2004.
  14. Lillibridge KM, Parsons R, Randle Y, Travassos da Rosa APA, Guzman H, Siirin M, Wuithiranyagool T, Hailey C, Higgs S, Bala A, Pascual R, Meyer T, Vanlandingham DL, TESH RB. The 2002 introduction of West Nile virus into Harris County, Texas, an area historically endemic for St. Louis encephalitis. Am J Trop Med Hyg 70:676-681, 2004.
  15. TESH RB, Watts DM, Sbrana E, Siirin M, Xiao S-Y. Experimental infection of ground squirrels (Citellus tridecemlineatus) with monkeypox virus: a small animal model of severe orthopoxvirus infection. Emerg Infect Dis 10:1563-1567, 2004.
  16. TESH RB, Siirin M, Guzman H, Travassos da Rosa APA, Wu X, Duan T, Lei H, Nunes MR, Xiao S-Y. Persistent West Nile virus infection in the golden hamster (Mesocricetus auratus): studies on its mechanism and possible implications for other flavivirus infections. J Infect Dis 192:287-295, 2005.
  17. Sbrana E, Mateo RI, Xiao SY, Popov VL, Newman PC, TESH RB. Clinical laboratory, virologic and pathologic changes in hamsters experimentally infected with Pirital virus (Arenaviridae): a rodent model of Lassa fever. Am J Trop Med Hyg 74:1096-1102, 2006.
  18. Ziegler SA, Lu L, Travassos da Rosa APA, Xiao S-Y, TESH RB. An animal model for studying the pathogenesis of chikungunya virus infection. Am J Trop Med Hyg 79:133-139, 2008.
  19. Mihindukulasuriya KA, Nguyen NL, Wu G, Huang HV, Travassos da Rosa APA, Popov VL, TESH RB, Wang D. Nyamanini and Midway viruses define a novel taxon of RNA viruses in the order Mononegavirales. J Virol 83:5109-5116, 2009.
  20. Presti R, Zhao G, Beatty WL, Mihindukulasuriya KA, Travassos APA, Popov VL, TESH RB, Virgin HW, Wang D. Sequencing and ultrastructural analyses define Quaranfil, Johnston Atoll and Lake Chad viruses as novel members of the family Orthomyxoviridae. J Virol (In press).

NIH Biosketch