The Research Histopathology Core (RHC)

Core LogoThe Research Histopathology Core (RHC) with laboratories in both Galveston National Laboratory and Basic Science Building provides analytical morphology related services to the research teams and educational programs at UTMB. The facility is equipped with the latest available instrumentation and operated by highly skilled personnel, who can assist with tissue preparation, immunohistochemistry, immunofluorescence, Insitu hybridization, including assay optimization, image analysis, digital photomicrography, and anatomical consultation. RHC provides an expanded service including coordinated histopathology support services or developing special protocols to fit your research needs for investigators engaging in research in emerging diseases. RHC looks forward to providing these services to fit your research needs and yielding high quality results.


AfrouzianDr. Marjan Afrouzian (Director) is the director of the Research Histopathology Core since 2015. She joined the department of Pathology in 2011 and started her career at UTMB as the director of Renal Pathology Services. Dr. Afrouzian earned her Medical Degree from Tehran University of Medical Sciences in Tehran, Iran. Her residency training in anatomical pathology was at the University of Calgary in Alberta, Canada. She completed research and clinical fellowships at multiple institutions including the University of North Carolina in Chapel Hill, the University of Alberta in Edmonton, and the Armed Forces Institute of Pathology in Washington, DC. She is American board certified in anatomical pathology with subspecialty in nephropathology and special interest in Genitourinary and Head and neck pathology. Her areas of research include organ transplantation including Thrombotic microangiopathy (TMA) in renal allografts and mechanisms of renal fibrosis in native kidney diseases.

Kenneth R. Escobar (Laboratory Manager) is an ASCP certified Histotechnologist with 30 years experience in clinical/diagnostic and research histopathology.

Services Available

Services included:

  • Tissue processing and embedding
  • Special microtomy and cryotomy
  • Routine and special staining
  • Immunohistochemistry, manually and automated
  • Immunohistochemistry assay development
  • Insitu Hybridization
  • TUNEL staining (manual)
  • Two color immunohistochemistry
  • Immunofluorescence staining

Equipment available for users includes:

  • Laser capture microdissection system
  • Tissue arrayer
  • Image analysis software
  • Microtome and cryostat
  • Photomicroscope
  • Light and epifluorescent microscope
  • Dissecting microscope with photo image software
  • Cytocentrifuge for preparation of cell smears


Research Histopathology Core Laboratory: (409) 747-0735
GNL Histopathology Core Laboratory: 409-266-6684
Fax: (409) 747-0725

Kenneth Escobar (Laboratory Manager):


The admixture of neoplastic spindle cells with extravasated red blood cells creates resemblance to Kaposi’s sarcoma. Used with permission from