In the early 1990s, UTMB launched a major new initiative to enhance its research. Since that time, six Sealy Centers for Research excellence have been established to maximize existing strengths and bring cutting-edge research to the university.
The Sealy Center for Vaccine Development was inaugurated in December, 2001. With 69 faculty members, the center incorporates the expertise of more than 100 cutting edge research programs currently at UTMB. These newly formed relationships, as well as collaborative relationships with investigators elsewhere, will help us translate laboratory findings to the bedside and beyond.
The overarching theme of the UTMB NIEHS Center is the role of oxidative stress in mediating the health effects of exposure to environmental factors. Investigators in the four Research Cores study the mechanisms by which reactive oxygen species are produced and detoxified (Biotransformation Research Core), modulate signaling pathways (Oxidative Stress and Signaling Research Core), damage DNA (DNA Repair and Mutagenesis Research Core), and are involved in the etiology of Asthma (Asthma Pathogenesis Research Core).
Airway inflammation researchers at UTMB play a major role in disease-oriented interdisciplinary research programs, including the Signaling in Airway Inflammation program project grant, the Proteomics Technologies in Airway Inflammation center grant, and the NIEHS Center in Environmental Toxicology.