Mechanisms associated with muscle function including protein synthesis, muscle metabolism, cell signaling, the role of essential amino acids and exercise associated with muscle growth and regeneration are investigated. Research efforts assist in the quantification and evaluation of rehabilitation outcomes, integrating research information and activities in muscle biology, motor control, and applied physiology with basic rehabilitation practice.
Nutrition and Muscle Metabolism
Overarching theme focuses on the role of nutritional supplements and physical activity in human muscle performance. Current studies examine amino acids in muscle protein synthesis and protein supplementation and exercise training contributions to muscle strength, growth, and function. Research in this area will improve our understanding of the physical, molecular, genetic, cellular, and tissue bases of muscle generation that to contribute to increase risk for injury and associated diseases.
The primary aim of MoTrPAC is to 'extensively catalogue the biological molecules affected by physical activity in people, identify some of the key molecules that underlie the systemic effects of physical activity, and characterize the function of these key molecules. This molecular map will help us understand how physical activity translates into better health'. Read more about the recently established University of Texas Adult Clinical Center (UTACC) for the Molecular Transducers of Physical Activity Consortium (MoTrPAC).
Research focuses on the mechanisms that lead to loss of muscle mass, strength, function, and independence in older adults. The overall goal of these investigations is to improve muscle function and functional recovery in older adults and determine prevention and treatment of muscle dysfunction and disability. The Claude D. Pepper Older Americans Independence Center, continuously funded since 2000, is a major project contributing to the area of muscle aging research.