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CPRIT Academic Research Program RFAs and Institutional Limits

Sep 5, 2018, 15:30 PM by Melodi Moore

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On August 17, 2018, the Cancer Prevention & Research Institute of Texas announced that several of the 19.2 (second round of 2019 Requests for Proposals (RFP)) would include Institutional Limits.  The following RFP descriptions include which limits apply to which RFPs.  UTMB faculty wishing to submit one of the limited RFPs will need to submit a biosketch and one-page abstract to Erica Huff on or before Sept 28, 2018 to be eligible for this round of limited submissions.  All questions should be directed to Ms. Huff.

Core Facility Support Awards (CFSA)

Solicits applications from institutions to establish or enhance core facilities (laboratory, clinical, population-based, or computer-based) that will directly support cancer research programs to advance knowledge of the causes, prevention, and/or treatment of cancer or improve quality of life for patients with and survivors of cancer. CPRIT is particularly interested in supporting core facilities that provide enabling services to cancer investigators from multiple Texas institutions. Note applications for this award mechanism are subject to institutional limits. Applicants are advised to consult with their institutions’ Office of Research and Sponsored Programs (or equivalent).

Award: Up to $3 million (total costs) for the first 2 years and up to $1M (total costs) for each subsequent year.

Maximum duration: Five years.

****An institution may submit only 1 application (1 new, 1 renewal, or 1 resubmission) under this RFA during this funding cycle.****

Early Translational Research Awards

Supports projects that "bridge the gap" between promising new discoveries achieved in the research laboratory and commercial development for a therapeutic, device, or diagnostic assay through activities including preclinical proof-of-principle data that demonstrate applicability to the planned clinical scenario and preclinical toxicology and formulation to de-risk the development of lead compounds or devices. Any not-for-profit institution that conducts research is eligible to apply for funding under this award mechanism. Presentation of a time line with stage gates for development is required. A public or private company is not eligible. Note applications for this award mechanism are subject to institutional limits. Applicants are advised to consult with their institutions’ Office of Research and Sponsored Programs (or equivalent).

Award: up to $ 2 million in total costs

Maximum duration: 1-2 years.

***The University of Texas Medical Branch Galveston limited to two (2) submissions***

High-Impact/High-Risk Research Awards (HIHR)

Provides short-term funding to explore the feasibility of high-risk projects that, if successful, would contribute major new insights into the etiology, diagnosis, treatment, or prevention of cancers. Note applications for this award mechanism are subject to institutional limits. Applicants are advised to consult with their institutions’ Office of Research and Sponsored Programs (or equivalent).

Award: Up to $200,000 (total costs)

Maximum duration: 2 years.

CPRIT is imposing a limit of 5 applications from an academic research institution

Collaborative Action Program to Reduce Liver Cancer Mortality in Texas: Collaborative Action Center Award

Supports a single Collaborative Action Center whose function will be to: (1) promote interactions and collaborations across the CAP Research Awards funded under the companion RFA, R-19.2 CAP:RA; (2) provide opportunities for academic content experts, health care providers and community stakeholders to exchange ideas and to explore new opportunities to impact the rise of hepatocellular cancer (HCC) in Texas and (3) educate health care providers and the public on best practices to alter the trajectory of HCC in Texas.  Note applications for this award mechanism are subject to institutional limits. Applicants are advised to consult with their institutions’ Office of Research and Sponsored Programs (or equivalent).

Award: CPRIT plans to make one award. Up to $3,000,000 in total costs.

Maximum duration: 5 years.

***An institution or organization may submit only 1 application under this RFA***

Collaborative Action Program to Reduce Liver Cancer Mortality in Texas: Investigator-Initiated Research Awards

Supports investigator-initiated research projects designed to understand the reasons for the increased incidence of HCC in Texas, to identify risk factors for cirrhosis and HCC, to identify biomarkers for HCC early detection, and to develop and implement prevention and early detection strategies. CAP Research Awardees (under this RFA) must agree to participate in the Collaborative Action Center initiatives including the CAP Steering Committee’s meetings and initiatives and the CAP program outreach and educational mission

Award: CPRIT plans to make multiple awards in response to this RFA. Up to $500,000 in total costs per year.

Maximum duration: 5 years.

***A PI may submit only 1 application under this RFA***

A PI may participate as a Co-PI on 1 or more applications as long as the applications are submitted by another Texas institution. A Co-PI may participate in only 1 application under this RFA except when the Co-PI is located at a separate Texas institution from the PI; • An individual may serve as a PI on no more than 3 active CPRIT Academic Research grants. Recruitment Grants and Research Training Awards do not count toward the 3- grant maximum; however, CPRIT considers MIRA Project Co-PIs equivalent to a PI. For the purpose of calculating the number of active grants, CPRIT will consider the number of active grants at the time of the award contract effective date (for this cycle expected to be August 31, 2019)