PCORI (Patient-Centered Outcomes Research Institute) was initially funded 2012 with an initial end-date of December 31, 2019.  In November 2019, the Institute was awarded an additional $2.4 billion to continue their work. 

PCORI takes a different approach to research by focusing on research topics, questions, and outcomes most important to patients and those who care for them.  They work closely with a range of healthcare stakeholders— including patients, caregivers, scientists, clinicians, health systems, and insurers—to guide their research funding.  PCORI requires that patients be engaged in the research, not as subjects but as partners who help determine what to study and how.

PCORI invites investigators to apply after submitting a well-written letter of intent (LOI).  See how to write a responsive PCORI LOI. 

The institute recently released their current broad funding announcementsand a list of upcoming announcements to help people plan.

Broad PCORI Funding Announcements -- Cycle 1 2020 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)

Seeks investigator-initiated applications for patient-centered comparative clinical effectiveness research (CER) projects aligned with our priority areas for research. This PFA covers the following four priority areas: Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; Communication and Dissemination Research, and Improving Healthcare Systems. Applications should address needs of patients, caregivers, clinicians, and other healthcare stakeholders in making personalized clinical decisions across a wide range of conditions, populations, and treatments.

LOI Due:                           February 4, 2020 5 pm ET
Application Due:              May 5, 2020 5 pm ET

Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 1 2020

Aims to fund studies that address high-priority methodological gaps in patient-centered outcomes research (PCOR) and comparative clinical effectiveness research (CER).

LOI Due:                           February 4, 2020 5 pm ET
Application Due:              May 5, 2020 5 pm ET

Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 1 2020

Move evidence developed with PCORI research funding toward practical use in improving health care and health outcomes.

LOI Due:                           February 4, 2020 5 pm ET
Application Due:              May 5, 2020 5 pm ET