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photo of Mark D. Bishop, PhD, PT

Mark D. Bishop, PT, PhD

Associate Professor

Department of Physical Therapy
University of Florida


Phone: (352) 273-2112

Lead Mentor

M. Robinson, PhD

Research Areas

Transition from acute to chronic pain and strategies for management of pain

  • 1989 University of Queensland Physical Therapy BS
  • 1998 University of Florida Health Science MS
  • 2002 University of Florida Rehabilitation Sciences PhD


Research Funding

Funding R01 AR055899-07 (George) 09/01/2016 08/31/2021 NIH/NIAMS Biopsychosocial Influence on Shoulder Pain Role: Principal Investigator UF site The goal is to determine efficacy of individualized management of cognitive and genetic interactions that place patients at risk of ongoing pain.

R01 AT006334 (Bishop) 05/01/2011 - 04/30/2017 NIH/NCCIH Central Mechanisms of Body Based Intervention for Musculoskeletal Pain Role: Principal Investigator The primary objective for this study is to compare the effect of manipulative and body-based interventions commonly used in the management of LBP on behavioral /psychophysical and cortical measures of pain sensitivity and central sensitization of pain.

R01 AT006334-S2 (Bishop) 05/01/2012 - 04/30/2017 NIH/NCCIH Central Mechanisms of Body Based Intervention for Musculoskeletal Pain - Supplement Role: Principal Investigator The primary objective for this study is to compare the effect of manipulative and body-based interventions commonly used in the management of LBP in veterans with low back pain.

F32 AT007729 (Gay) 09/14 09/16 NIH/NCCAM Central mechanisms of manipulative and body based interventions: training program This fellowship training program for a chiropractic physician (1) focuses on a CAM intervention that is frequently provided to the American public by chiropractors for low back pain, and (2) investigates a potential neurophysiologic mechanism underlying pain relief, which is why the intervention is most frequently employed. Role: Mentor (Charles Gay Post-doctoral fellow)

K01AE054331 (Bishop) 07/03/2008-08/31/13 NIAMS Neurobiological mechanisms of body based intervention for musculoskeletal pain The specific aims of this research proposal are to 1) quantify psychological and neurophysiological factors that are associated with development of acute experimental endogenous pain after exercise and 2) determine if early application of manual therapies effectively modify those factors that are believed to be linked to the development of chronic pain syndromes Role: Principal Investigator

Publications (past 5 years)

Bishop MD, Coronado RA, Hill A, Alappattu MJ. Where we have been and where we are going: a content analysis of manuscripts published in the Journal of Women's Health Physical Therapy from 2005-2015. In press

Horn ME, Brennan GP, George SZ, Harman JS, Bishop MD. A value proposition for early physical therapist management of neck pain: A retrospective cohort analysis. BMC Health Serv Res, 2016 Jul 12;16:253 PMCID: PMC4942887

Elliott JM, Owen M, Bishop MD, Sparks C, Tsao H, Walton DM, Weber II KA, Wideman T. Measuring Pain for Patients Seeking Physical Therapy: Can Functional Magnetic Resonance Imaging (fMRI) Help? Phys Ther. 2016, Jul 28.

Villifane J, 10 outpatient sessions of Nintendo Wii Fit for Balance Rehabilitation are enough in Patients with Parkinson's Disease: A prospective controlled cohort Study. J Bodyw Mov Ther. 2016 Jan;28(2):607-12

Neville C, Beneciuk J, Bishop M, Alappattu MJ. Analysis of Physical Therapy Intervention Outcomes for Urinary Incontinence in Women Over Age 65 in Outpatient Clinical Settings. Topics in Ger Rehab.2016 32:4.

Villafañe JH, Pirali C, Dughi S, Testa A, Manno S, Bishop MD, Negrini S. Association between malnutrition and Barthel Index in a cohort of hospitalized older adults. J Phys Ther Sci. 2016, 28: 607-612 PMCID: PMC4793019

Alappattu MJ, Neville C, Beneciuk JB, Bishop MD. The prevalence of urinary incontinence among patients reporting to outpatient physical therapy. Physiother Theory Prac. 2016 Feb;32(2):107-12.

Simon CB, Lentz TA, Bishop MD, Riley JL 3rd, Fillingim RB, George SZ. Comparative Associations of Working Memory and Pain Catastrophizing With Chronic Low Back Pain Intensity. Phys Ther. 2016 Jul;96(7):1049- 56

Light KE, Bishop MD, Wright T. Telephone Calls Make a Difference in Home Balance Training Outcomes: A Randomized Trial. J Geriatr Phys Ther. 2016 July-Sep; 39(3):97-101.

Horn ME, Brannan G, George SZ, Harmon J, Bishop MD. Clinical Outcomes, Utilization and Charges in Persons with Neck Pain Receiving Guideline Adherent Physical Therapy. Eval Health Prof. 2016 Dec;39(4): 421-434.

Bishop MD, Torres-Cueco R, Gay CW, Lluch-Girbés E, Beneciuk JM, Bialosky JE. What effect can manual therapy have on a patient's pain experience? Pain Management. 2015;5(6):455-64

Gay CW, Papuga MO, Bishop MD, Dougherty P. The frequency and reliability of cortical activity using a novel strategy to present pressure pain stimulus over the lumbar spine. J Neurosci Methods. 2015 Jan 15;239:108-13 PMCID: PMC4268025

Gay CW, Horn ME, Bishop MD, Robinson ME, Bialosky JE. Investigating Dynamic Pain Sensitivity in the Context of the Fear Avoidance Model. Eur J Pain. 2015 Jan;19(1):48-58.

Coronado RA, Bialosky JE, Bishop MD, Riley JL, Robinson ME, Michener LA, George SZ. The Comparative Effects of Spinal and Peripheral Thrust Manipulation and Exercise on Pain Sensitivity and the Relation to Clinical Outcome: A Mechanistic Trial Using a Shoulder Pain Model. J Orthop Sports Phys Ther. 2015 Mar 4:1-44 PMCID: PMC4789758

Alappattu MJ, George SG, Robinson ME, Fillingim R, Moawad N, Weber LeBrun E, Bishop MD. Painful intercourse is significantly associated with evoked pain perception and cognitive aspects of pain in women with pelvic pain. Sex Med. 2015 Mar; 3(1): 1423. PMCID: PMC4380910

Horn ME, Brannan GP, George SZ, Harman JS, Bishop MD. Description of Common Clinical Presentations and Associated Short-Term Physical Therapy Clinical Outcomes and Utilization in Patients with Neck Pain. Arch Phys Med Rehabil. 2015 Oct;96(10):1756-62

Simon CB, Riley JL 3rd, Fillingim RB, Bishop MD, George SZ. Age Group Comparisons of TENS Response among Individuals with Chronic Axial Low Back Pain, J Pain. 2015 Dec;16(12):1268-79 PMCID: PMC4666741

Hass CJ, Bishop MD, Moscovich M, Stegemöller EL, Skinner J, Malaty IA, Shukla AW, McFarland N, Okun MS. Defining the Clinically Meaningful Difference in Gait Speed in Persons With Parkinson Disease. J Neurol Phys Ther. 2014 Oct; 38(4):233-8.

Gay CW, Robinson ME, George SZ, Perlstein WM, Bishop MD. Immediate Changes After Manual Therapy in Resting-State Functional Connectivity as Measured by Functional Magnetic Resonance Imaging in Participants With Induced Low Back Pain. J Manipulative Physiol Ther. 2014 37(9):614-27. PMCID: PMC4248017

Valencia C, Fillingim RB, Bishop MD, Wu SS, Wright TW, Moser M, Farmer K, George SZ. Investigation of central pain processing in postoperative shoulder pain and disability. Clin J Pain. 2014 Sep;30(9):775-86. PMCID: PMC3954955

Hannibal KE, Bishop MD. Chronic Stress, Cortisol Dysfunction, and Pain: A Psychoneuroendocrine Rationale for Stress Management in Pain Rehabilitation. Phys Ther. 2014 Dec;94(12):1816-25. PMCID: PMC4263906

Gay CW, Bishop MD. Research on placebo analgesia is relevant to clinical practice. Chiropractic Man Ther. 2014 22:6. PMCID: PMC3917618

Pérez HI, Perez JLA, Martinez AG, La Touche R, Lerma Lara S, Gonzalez NC Perez HA, Bishop MD, Fernández-Carnero J. Is one better than another? : a randomized clinical trial of manual therapy for patients with chronic neck pain. Man Ther 2014 Jun;19(3):215-21

Horn ME, Alappattu MJ, Gay CW, Bishop MD. Fear of Severe Pain Mediates Sex Differences in Pain Sensitivity Responses to Thermal Stimuli. Pain Res Treatment. 2014,;2014:897953. PMCID:PMC3913346

Bishop MD, Mintken PE, Bialosky JE, Cleland JA. Patient Expectations of Benefit from Interventions for Neck Pain and Resulting Influence on Outcomes. J Orthop Sports Phys Ther. 2013 43(7):457-65. PMID:2350834

Gay CW, Alappattu MJ, Coronado RA, Horn ME, Bishop MD. Effect of a single session of muscle-biased therapy on pain sensitivity: a systematic review and meta-analysis of randomized controlled trials. J Pain Res. 2013;6:7-22. doi: 10.2147/JPR.S37272. PMCID: PMC3569047

Horn ME, Bishop MD. Flexion Relaxation Ratio Not Responsive to Acutely Induced Low Back Pain from a Delayed Onset Muscle Soreness Protocol. ISRN Pain, 2013, Feb 25;2013:617698. doi: 10.1155/2013/617698 PMCID: PMC4893392

Beneciuk JM, Bishop MD, Fritz JM, Robinson ME, Asal NR, Nisenzon AN, George SZ. The STarT Back Screening Tool and Individual Psychological Measures: Evaluation of Prognostic Capabilities for Low Back Pain Clinical Outcomes in Outpatient Physical Therapy Settings. Phys Ther. 2013 Mar;93(3):321-33. doi: 10.2522/ptj.20120207. PMCID: PMC3588106

Villafañe JH, Bishop MD, Fernández-de-las-Peñas C, Langford D. Radial nerve mobilisation had bilateral sensory effects in people with thumb carpo-metacarpal osteoarthritis: a randomised trial. J Physiother. 2013 Mar;59(1):25-30. doi: 10.1016/S1836-9553(13)70143-7.

La Touche R, París-Alemany A, Mannheimer JS, Angulo-Díaz-Parreño S, Bishop MD, Lopéz-Valverde- Centeno A, von Piekartz H, Fernández-Carnero J. Does Mobilization of the Upper Cervical Spine Affect Pain Sensitivity and Autonomic Nervous System Function in Patients With Cervico-craniofacial Pain?: A Randomized-controlled Trial. Clin J Pain. Clin J Pain. 2013 Mar;29(3):205-15. doi: 10.1097/AJP.0b013e318250f3cd.

Anderson RJ, Craggs JG, Bialosky JE, Bishop MD, George SZ, Staud R, Robinson ME. Temporal summation of second pain: Variability in responses to a fixed protocol. Eur J Pain. 2013 Jan;17(1):67-74 PMCID: PMC3502719

Bishop MD, Romero S, Patterson TS, Singletary FF, Light KE. Exploration of patient centered success criteria and clinically measured improvement during falls rehabilitation. J Ger Phys Ther. 2012 Oct-Dec;35(4):181- 90

Bialosky JE, Simon CB, Bishop MD, George SZ. Basis for spinal manipulative therapy: A physical therapist perspective. J Electromyogr Kinesiol. 2012 Oct;22(5):643-7.

Coronado RA, Gay CW, Bialosky JE, Bishop MD, George SZ, Mann G. Changes in Pain Sensitivity following Spinal Manipulation: a Systematic Review and Meta-Analysis. J Electro Kines. 2012 Oct;22(5):752-67 PMCID:PMC3349049

Gay CW, Bishop MD, Beres J. Thoracic Myelopathy, a vague manifestation: Clinical Presentation of a Patient at a Chiropractic Clinic. J Chiro Med. 2012 Jun;11(2):115-20 PMCID:PMC3368975

Bishop MD, George SZ, Robinson ME. Dynamic, but not static, pain sensitivity predicts exercise-induced muscle pain: Covariation of temporal sensory summation and pain intensity. Neurosci Lett. 2012; 562 (1), 1-4

Sindhu BS, Lehman LA, Tarima S, Bishop MD, Hart DL, Klein MR, Shivakoti M, Wang YC. Influence of fear-avoidance beliefs on functional status outcomes for people with musculoskeletal conditions of the shoulder. Phys Ther. 2012 Aug;92(8):992-1005.

Villafañe JH, Silva GB, Bishop MD, Fernandez-Carnero J. Radial nerve mobilization decreases pain sensitivity and improves motor performance in patients with thumb carpometacarpal osteoarthritis: a randomized, controlled trial. Arch Phys Med Rehab. 2012 Mar;93(3):396-403

Bialosky JE, Bishop MD, Robinson ME, Price DD, George SZ. Heightened Pain Sensitivity in Individuals with Signs and Symptoms of Carpal Tunnel Syndrome and the Relationship to Clinical Outcomes Following a Manual Therapy Intervention Manual Therapy. Man Ther. 2011 Dec;16(6):602-8

Bishop MD, Horn ME, Lott DJ, Arpan I, George SZ. Magnitude of spinal muscle damage is not statistically associated with exercise-induced low back pain intensity. Spine J. 2011 Dec;11(12):1135-42

Dalton E, Bishop MD, Tillman MD, Hass CJ. Simple change in initial standing position enhances the initiation of gait. Med Sci Sport Exer. 2011 Dec;43(12):2352-8.

Romero S, Bishop MD, Velozo C, Light K. Minimum Detectable Change of the Berg Balance Scale and Dynamic Gait Index in Geriatric Patients with Gait and Balance Deficits. J Ger Phys Ther. 2011 Jul- Sep;34(3):131-7

Alappattu MJ, Bishop MD. Application of the fear avoidance model to chronic pelvic pain. Phys Ther. 2011 Oct;91(10):1542-50 PMCID:PMC3185223

Bishop MD, Horn ME, George SZ. Exercise-induced pain intensity predicted by pre-exercise fear of pain and pain sensitivity. Clin J Pain. 2011 Jun;27(5):398-404. PMCID: PMC3092017

Bishop MD, Beneciuk J, George SZ. Reduction in temporal sensory summation after spinal manipulation. Spine J. 2011 May;11(5):440-6. PMCID: PMC3092807

Alappattu MJ, Bishop MD, Bialosky JE, George SZ, Robinson ME. Stability of Behavioral Estimates of Activity- Dependent Modulation of Pain. J Pain Res. 2011:4 17 PMCID: PMC3141831

Ko MS, Bishop MD, Behrman AL. Effects of Limb Loading on Gait Initiation in Persons with Moderate Hemiparesis. Topics Stroke Rehab. 2011 18 (3): 258-268

Patterson TS, Bishop MD, McGuirk TE, Sethi A, Richards LG. Reliability of Upper Extremity Kinematics While Performing Different Tasks in Individuals Post Stroke. J Motor Behav. 2011, 43(2):121-30. doi: 10.1080/00222895.2010.548422.

Bishop MD, Horn ME, George SZ, Robinson ME. Self-reported pain and disability outcomes from an endogenous model of muscular back pain. BMC Musculoskeletal Disorders 2011, Feb 2:12:35.

Bialosky JE, Bishop MD, Robinson ME, George SZ. Placebo Response to Manual Therapy: Something out of nothing? J Man Manip Ther. 2011 Feb;19(1):11-9. PMCID: PMC3172952

Bishop MD, Bialosky JE, Cleland JA. Patient expectations of benefit from common interventions for low back pain and effects on outcome: secondary analysis of a clinical trial of manual therapy interventions. J Man Manip Ther. 2011 Feb;19(1):20-5. PMCID: PMC3172953

Complete List of Published Work in MyBibliography

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USC: University of Southern California logo
UTMB: University of Texas Medical Branch logo