Stroke recovery, motor control, non-invasive brain stimulation, gait, cardiovascular health post-stroke
- 1985 Daemen College, Buffalo NY Physical Therapy BS
- 1993 University of North Carolina at Chapel Hill Human Movement Science MS
- 2004 University of Southern California Biokinesiology PhD
Current Research Funding
R21AG053736 (Clark) 6/01/2017 - 5/31/2019 National Institutes of Health. Combining tDCS and neurorehabilitation to treat age-related deficits of mobility and cognition. The purpose of this study is to demonstrate preliminary efficacy and feasibility of a novel therapeutic intervention that is designed to enhance mobility and cognition via neuroplasticity of prefrontal cerebral circuits in older adults with mobility deficits and cognitive/executive dysfunction.
15MCPRP25670037 (Rose) 07/01/2015 - 06/30/2018. American Heart Association. A Novel Strategy to Improve Gait and Falls Self-Efficacy Post-Stroke. The purpose of this study is to compare the efficacy of two rehabilitation approaches on gait speed: a novel, experimental intervention that uses backward walking as the primary training modality and a standard of care comparison intervention of forward walking.
N2051-P (Rose) 4/01/2016 - 1/31/2019 VA RR&D Biofeedback to Increase Propulsion during Walking after Stroke. The purpose of this study is to test the hypothesis that biofeedback as an adjuvant to therapists’ verbal feedback will improve propulsion and enhance walking function post-stroke.
N2004-R (Rose) 6/01/2016 - 5/31/2020 VA RR&D. A Novel Strategy to Decrease Fall Incidence Post-Stroke. The purpose of this study is to test a novel gait training strategy, backward walking, to improve gait speed, improve balance and decrease fall incidence post-stroke.
B1149R (Clark) 6/1/2014 - 5/31/2019 VA RR&D. Rehabilitation of Corticospinal Control of Walking after Stroke: The ABCs of Walking. The purpose of this clinical trial is to determine changes in the cortical control of walking following a gait training intervention. Role: Co-Investigator
B9252-C (Daly) 7/2014 - 6/2019 VA RR&D. Brain Rehabilitation Research Center of Excellence. Role: Co-Investigator and Locomotor Initiative Co-Coordinator
Chatterjee SA, Daly JJ, Porges EC, Fox EJ, Rose DK, McGuirk TE, Otzel DM, Butera KA, and Clark DJ. Mobility function and recovery after stroke: preliminary insights from sympathetic nervous system activity. Journal of Neurologic Physical Therapy, in press, 2018.
Hawkins KA, Fox EJ, Daly JJ, Rose DK, Christou EA, McGuirk TE, Otzel DM, Butera KA, Chatterjee SA, Clark DJ. Prefrontal Over-activation during Walking in People with Mobility Deficits: Interpretation and Functional Implications. 2018. Human Movement Science. 59:46-55.
Rose DK, DeMark L, Fox EJ, Clark DJ, Wludyka, P. A Backward Walking Training Program to Improve Balance and Mobility in Acute Stroke: A Pilot Randomized Controlled Trial. Journal of Neurologic Physical Therapy. 2018. 42(1):12-21.
Rose DK, Nadeau S, Wu SS, Tilson JK, Dobkin BH Pei, Q, Duncan PW. Locomotor Training and Strength and Balance Exercises for Walking Recovery Post-Stroke: Response to Number of Training Sessions. Physical Therapy. 2017. 97(11):1066-1074.
Hershberg JA, Rose DK, Tilson JK, Brutsch BM, Correa AC, Gallichio J, McLeod MA, Moore CA, Wu SS Duncan PW, Behrman AL for the LEAPS Investigative Team. Interface of clinical decision-making with study protocols for knowledge translation of a walking recovery trial. Journal of Neurologic Physical Therapy. 2017. 41(1):59-67.
Fox EJ, Foster HE, DeMark L, Spigel PM, Rose DK. The effects of backward walking training on balance and mobility in a person with chronic incomplete spinal cord injury: A case report. Physiotherapy Theory and Practice. 2016.Oct;32(7):536-45.
Nadeau S, Rose DK, Dobkin BH, Wu SS, Schofield R, Dai Y, Duncan PW. Likelihood of Myocardial Infarction during Stroke Rehabilitation Preceded by Cardiovascular Screening and an Exercise Tolerance Test: The LEAPS Experience. International Journal of Stroke. 2014. 9(8): 1097-1104.
Clark DJ, Rose DK, Ring SA, Porges EC. Utilization of central nervous system resources for preparation and performance of complex walking tasks in older adults. Front. Aging Neurosci. 2014. 6.:217.
Rose DK, Patten C McGuirk T, Lu X, Triggs WJ. Does Inhibitory Repetitive Transcranial Magnetic Stimulation Augment Functional Task Practice to Improve Arm Recovery in Chronic Stroke? Stroke Treatment and Research. 2014;2014:305236.
Rose DK, Being Deliberate in Post-Acute Stroke: Strategies to Redeem the Time. Topics in Stroke Rehabilitation. 2014.21(4):281-289.
Dobkin BH, Nadeau S, Wu SS, Rose DK, Bowden MA, Studenski S, Lu X, Duncan PW. Prediction of responders to the interventions of the Locomotor Experience Applied Post-Stroke Clinical Trial. Journal of Rehabilitation and Development. 2014. 51(1):39-50.