photo of older people engaged in physical sctivity and falls studies

Clinical Trials

The Sealy Center on Aging (SCoA) currently supports 22 clinical trials and is proactively looking for industry trial opportunities. This has been the result of a deliberate effort to increase clinical trial capacity and improve the processes that facilitate clinical trial initiation, regulatory support, and coordination. The Center increased the pool of study coordinators and restructured the Clinical Research Resource Core and Volunteer Registry to better support investigators in their regulatory needs and subject recruitment.

Current Studies at the Sealy Center on Aging

SCoA's participation in two large clinical trials funded by the NIH and PCORI include:

  • the ASPREE trial of aspirin to improve functional and cognitive outcomes in older adults
  • the STRIDE Study on fall prevention in older adults living in the community using a pragmatic approach.

The work on our electronic health record (EHR) system conducted as part of the UT System grant has positioned the Center at the forefront for use of our EHR for clinical trials, leading to our inclusion as a clinical site in the STRIDE Study.

Volunteer for Research

Volunteer Opportunities

The Volunteer Registry
Phone: 1-800-298-7015

Senior volunteers (age 55 and over) are invited to join the Volunteer Registry. The Registry is a list of volunteers interested in contributing to research studies on the health and well-being of older persons. Aging research participants also have a chance to learn more about their own health.

Pepper Center Studies
Phone: 1-800-298-7015

Senior volunteers (age 60 and over) are invited to participate in research on muscle function, fitness, and health and well-being of older persons. Muscle strength will be studied in terms of the effect of exercise, drugs, hormones and nutrition.

Open Trials

Clinical Trials in Open Recruitment

Principal Investigator

IRB Number

Project Title

Open Recruitment




Self-monitoring activity: a randomized trial of game-oriented applications (SMARTGOAL)

Breast Cancer Survivors Only

Eloisa Martinez



Prevalence of Malnutrition and/or Sarcopenia on Hospital Admission

At UTMB Hospital

Shawn Goodlett



The Effects of a 4-week PT Intervention on Posture, Physical Intervention, Pulmonary Function, and Patient Perspectives

At PT Clinics

Lynn Hughes



Identifying Therapeutic Targets of Accelerated Sarcopenia

Diabetic Subjects Only

Paula Skinkis



Support Group Toolkit for Breast Cancer Survivors

Breast Cancer Survivors Only

Eloisa Martinez



Translating Muscle anabolic Strategies into Interventions to Accelerate Recovery from Hospitalization in Geriatric Patients

At UTMB Hospital

Shawn Goodlett



The Physiological Effects of Intranasal Oxytocin on Sarcopenic Obesity

BMI > 42 Only

Tutu (Adetutu Odejimi)



Bed Rest in Accelerated Sarcopenia Study

Diabetic Subjects Only

Paula Skinkis



Combining Testosterone Therapy and Exercise to Improve Function Post Hip Fracture

Post Hip Fracture women Only

Eloisa Martinez



Molecular Transducers of Physical Activity Consortium (MoTrPAC) University of Texas Adult Clinical Center

Pre-Recruitment Activities

Jessica Spahn



A Phase I Randomized Clinical Trial of In-hospital and Post-hospital Whey Protein vs. Low Quality Protein vs. Isocaloric Placebo Supplementation to Improve Recovery from Hospitalization in Older Adults in Older Adults

At UTMB Hospital

Shawn Goodlett

Past Trials

Clinical Trials No Longer Recruiting

IRB Number

Project Title


Nutrition & Exercise to Improve Protein Metabolism & Prevent Sarcopenia in Aging


A Non-Invasive Assessment of Skeletal Muscle Loss in Cancer Patients


Effects of Amino Acids on Regional Lipid Metabolism


Pilot Study to Discover Predictors of Muscle Loss with Aging


Skeletal Muscle Microvascular Perfusion and the Obesity Paradox in CHF


Role of Skeletal Muscle Nitric Oxide Production in Age-Related Fatigue and Fatigability


Nutrition and Anabolic Interventions in Cancer Cachexia - Head/Neck Cancer


Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly


ASPREE: ASPirin in Reducing Events in the Elderly


Feasibility Study of Post-hospitalization Interventions to Improve Physical Function in Older Adults (PACE)


IMPACT: Inactivity Monitoring and Physical Activity Controlled Trial


STEP AND GO: Study of Technology-based Exercise Promotion


Open Acute Study: Effects of Post-Exercise Whey Peptide on Muscle mTOR Signaling and Protein Synthesis in Healthy Young and Older Adults


Fall risk reduction in the elderly through the Physical Therapy management of incontinence: a pilot study


Effect of Specific Amino Acids on Human Muscle Protein Synthesis


Economic and Humanistic Impact of Low Peak Inspiratory Flow Rate (PIFR) In COPD Patients: An Observational Analysis


Nutrient Sensing and Signaling in Aging Muscle


Strategies to Reduce Injuries and Develop confidence in Elders (STRIDE)


Effect of Whey Protein Hydrolysate on Human Muscle Protein Synthesis

Site managed by UTMB Sealy Center on Aging • Date Updated: October 2018