Clinical Trials

The Sealy Center on Aging (SCoA) currently supports 22 clinical trials and is proactively looking for industry trial opportunities. This has been the result of a deliberate effort to increase clinical trial capacity and improve the processes that facilitate clinical trial initiation, regulatory support, and coordination. The Center increased the pool of study coordinators and restructured the Clinical Research Resource Core and Volunteer Registry to better support investigators in their regulatory needs and subject recruitment.

Current Trials

SCoA's participation in two large clinical trials funded by the NIH and PCORI include:

The work on our electronic health record (EHR) system conducted as part of the UT System grant has positioned the Center at the forefront for use of our EHR for clinical trials, leading to our inclusion as a clinical site in the STRIDE Study.

Volunteer Opportunities

The Volunteer Registry
Phone: 1-800-298-7015

Senior volunteers (age 55 and over) are invited to join the Volunteer Registry. The Registry is a list of volunteers interested in contributing to research studies on the health and well-being of older persons. Aging research participants also have a chance to learn more about their own health.

Pepper Center Studies
Phone: 1-800-298-7015

Senior volunteers (age 60 and over) are invited to participate in research on muscle function, fitness, and health and well-being of older persons. Muscle strength will be studied in terms of the effect of exercise, drugs, hormones and nutrition.

Clinical Trials in Open Recruitment

Principal Investigator

IRB Number

Project Title

Open Recruitment

Contact

Volpi

#14-0113

ASPREE Cancer Endpoints Study

ASPREE Subjects Only

Eloisa Martinez

Lyons

#14-0376

Self-monitoring activity: a randomized trial of game-oriented applications (SMARTGOAL)

Breast Cancer Survivors Only

Eloisa Martinez

Volpi

#14-0527

Prevalence of Malnutrition and/or Sarcopenia on Hospital Admission

At UTMB Hospital

Shawn Goodlett

Hughes

#15-0098

The Effects of a 4-week PT Intervention on Posture, Physical Intervention, Pulmonary Function, and Patient Perspectives

At PT Clinics

Lynn Hughes

Volpi

#15-0229

Identifying Therapeutic Targets of Accelerated Sarcopenia

Diabetic Subjects Only

Paula Skinkis

Swartz

#16-0040

Support Group Toolkit for Breast Cancer Survivors

Breast Cancer Survivors Only

Eloisa Martinez

Deer

#16-0146

Translating Muscle anabolic Strategies into Interventions to Accelerate Recovery from Hospitalization in Geriatric Patients

At UTMB Hospital

Shawn Goodlett

Volpi

#16-0374

The Physiological Effects of Intranasal Oxytocin on Sarcopenic Obesity

BMI > 42 Only

Tutu (Adetutu Odejimi)

Volpi

#17-0064

Bed Rest in Accelerated Sarcopenia Study

Diabetic Subjects Only

Paula Skinkis

Volpi

#17-0349

Combining Testosterone Therapy and Exercise to Improve Function Post Hip Fracture

Post Hip Fracture women Only

Eloisa Martinez

Rasmussen

#18-0057

Molecular Transducers of Physical Activity Consortium (MoTrPAC) University of Texas Adult Clinical Center

Pre-Recruitment Activities

Jessica Spahn

Volpi

TBD

A Phase I Randomized Clinical Trial of In-hospital and Post-hospital Whey Protein vs. Low Quality Protein vs. Isocaloric Placebo Supplementation to Improve Recovery from Hospitalization in Older Adults in Older Adults

At UTMB Hospital

Shawn Goodlett

Clinical Trials No Longer Recruiting

IRB Number

Project Title

Closed Recruitment

#08-085

Nutrition & Exercise to Improve Protein Metabolism & Prevent Sarcopenia in Aging

data analysis and manuscript writing

#09-150

A Non-Invasive Assessment of Skeletal Muscle Loss in Cancer Patients

data analysis and manuscript writing

#09-197

Effects of Amino Acids on Regional Lipid Metabolism

data analysis and manuscript writing

#09-200

Pilot Study to Discover Predictors of Muscle Loss with Aging

data analysis and manuscript writing

#09-203

Skeletal Muscle Microvascular Perfusion and the Obesity Paradox in CHF

data analysis and manuscript writing

#09-213

Role of Skeletal Muscle Nitric Oxide Production in Age-Related Fatigue and Fatigability

data analysis and manuscript writing

#10-207

Nutrition and Anabolic Interventions in Cancer Cachexia - Head/Neck Cancer

data analysis and manuscript writing

#11-091

Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly

data analysis and manuscript writing

#11-301

ASPREE: ASPirin in Reducing Events in the Elderly

study visits ongoing for several years

#13-038

Feasibility Study of Post-hospitalization Interventions to Improve Physical Function in Older Adults (PACE)

data analysis and manuscript writing

#13-071

IMPACT: Inactivity Monitoring and Physical Activity Controlled Trial

data analysis and manuscript writing

#13-0285

STEP AND GO: Study of Technology-based Exercise Promotion

Healthy Subject Only

#13-0390

Open Acute Study: Effects of Post-Exercise Whey Peptide on Muscle mTOR Signaling and Protein Synthesis in Healthy Young and Older Adults

data analysis and manuscript writing

#14-0142

Fall risk reduction in the elderly through the Physical Therapy management of incontinence: a pilot study

data analysis and manuscript writing

#14-0333

Effect of Specific Amino Acids on Human Muscle Protein Synthesis

data analysis and manuscript writing

#15-0128

Economic and Humanistic Impact of Low Peak Inspiratory Flow Rate (PIFR) In COPD Patients: An Observational Analysis

data analysis and manuscript writing

#15-0226

Nutrient Sensing and Signaling in Aging Muscle

data analysis and manuscript writing

#16-0092

Strategies to Reduce Injuries and Develop confidence in Elders (STRIDE)

data analysis and manuscript writing

#17-0086

Effect of Whey Protein Hydrolysate on Human Muscle Protein Synthesis

data analysis and manuscript writing

 

Site managed by UTMB Sealy Center on Aging • Date Updated: April 2018