Clinical Trials

The Sealy Center on Aging (SCoA) currently supports 22 clinical trials and is proactively looking for industry trial opportunities. This has been the result of a deliberate effort to increase clinical trial capacity and improve the processes that facilitate clinical trial initiation, regulatory support, and coordination.

The Center increased the pool of study coordinators and restructured the Clinical Research Resource Core and Volunteer Registry to better support investigators in their regulatory needs and subject recruitment.

photos of clinical trials participants and researchers

Current Trials

SCoA's participation in two large clinical trials funded by the NIH and PCORI include:

The work on our electronic health record (EHR) system conducted as part of the UT System grant has positioned the Center at the forefront for use of our EHR for clinical trials, leading to our inclusion as a clinical site in the STRIDE Study.

IRB Number Project Title Open Recruitment
#09-203 Skeletal Muscle Microvascular Perfusion and the Obesity Paradox in CHF CHF Only
#12-153 The Effect of Sildenafil and Tadalafil on Skeletal Muscle and Perceptual Fatigue Healthy Older Adults Only
#13-038 Feasibility Study of Post-hospitalization Interventions to Improve Physical Function in Older Adults At UTMB Hospital
#13-0285 STEP AND GO: Study of Technology-based Exercise Promotion Healthy Subject Only
#14-0113 ASPREE Cancer Endpoints Study ASPREE patients Only
#14-0142 Fall risk reduction in the elderly through the Physical Therapy management of incontinence: a pilot study At PT Clinics
#14-0527 Prevalence of Malnutrition and/or Sarcopenia on Hospital Admission At UTMB Hospital
#14-0527 Self-monitoring activity: a randomized trial of game-oriented applications (SMARTGOAL) Healthy Subjects Only
#15-0098 Feasibility of a Post-Hospitalization PT Intervention in Patients with Pneumonia At PT Clinics
#15-0128 Economic and Humanistic Impact of Low Peak Inspiratory Flow Rate (PIFR) In COPD Patients: An Observational Analysis At UTMB Hospitalized Patients Only
#15-0226 Nutrient Sensing and Signaling in Aging Muscle Healthy Subjects Only
IRB#- Brigham and Women’s Hospital- STRIDE- Strategies to Reduce Injuries and Develop confidence in Elders At Primary Care Clinics

IRB Number Project Title Closed Recruitment
#08-085 Nutrition & Exercise to Improve Protein Metabolism & Prevent Sarcopenia in Aging data analysis and manuscript writing
#09-150 A Non-Invasive Assessment of Skeletal Muscle Loss in Cancer Patients data analysis and manuscript writing
#09-197 Effects of Amino Acids on Regional Lipid Metabolism data analysis and manuscript writing
#09-200 Pilot Study to Discover Predictors of Muscle Loss with Aging data analysis and manuscript writing
#09-213 Role of Skeletal Muscle Nitric Oxide Production in Age-Related Fatigue and Fatigability data analysis and manuscript writing
#10-207 Nutrition and Anabolic Interventions in Cancer Cachexia - Head/Neck Cancer data analysis and manuscript writing
#11-091 Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly data analysis and manuscript writing
#11-301 ASPREE: ASPirin in Reducing Events in the Elderly study visits ongoing for several years
#13-071 IMPACT: Inactivity Monitoring and Physical Activity Controlled Trial data analysis and manuscript writing
#13-0390 Open Acute Study: Effects of Post-Exercise Whey Peptide on Muscle mTOR Signaling and Protein Synthesis in Healthy Young and Older Adults data analysis and manuscript writing
#14-0333 Effect of Specific Amino Acids on Human Muscle Protein Synthesis data analysis and manuscript writing

Volunteer Opportunities

The Volunteer Registry
Phone: 1-800-298-7015

Senior volunteers (age 55 and over) are invited to join the Volunteer Registry. The Registry is a list of volunteers interested in contributing to research studies on the health and well-being of older persons. Aging research participants also have a chance to learn more about their own health.

Pepper Center Studies
Phone: 1-800-298-7015

Senior volunteers (age 60 and over) are invited to participate in research on muscle function, fitness, and health and well-being of older persons. Muscle strength will be studied in terms of the effect of exercise, drugs, hormones and nutrition.

Site managed by UTMB Sealy Center on Aging • Date Updated: 11-FEB-2016