Description: Outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens.
Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes.
Vaccinology: An Essential Guide is a perfect tool designed for undergraduates and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.
About the Editors
Drs. Alan Barrett and Gregg Milligan are world-renowned experts in vaccine development and viral immunology. Dr. Barrett, a recognized leader in the biology of flaviviruses, researches tropical virus diseases such as dengue, West Nile, yellow fever and Japanese encephalitis. He has made important contributions to molecular aspects of immunogens and preclinical development of candidate vaccines for these diseases, and studies on the current yellow fever 17D vaccine. Dr. Milligan's research focuses on the innate and adaptive immune responses to herpesviruses. Additionally, he examines the linkage of the innate immune response to vaccines with the development of adaptive immune responses and the role of tissue-resident immune memory cells in protection against virus infections and disease.
Eleven of Tweleve UTMB Contributing Authors
Front Row: Richard Rupp MD, David Walker MD, Bridget Hawkins PhD MBA, Christine Arcari PhD MPH
Back Row: Jai Rudra PhD, Gregg Milligan PhD, Alfredo Torres PhD, Jere McBride PhD, David Bealsey PhD, Nigel Bourne PhD, Alan Barrett PhD.
Not pictured: Dennis Trent PhD