Project 3: Toxicology of Petrogenic PAH in the
Gulf-Oil Spill
- Evaluate the toxicity of selected alkylated and oxygenated PAH, and PAH extracts from seafood using validated cell-based assay systems
- Elucidate the metabolism of the petrogenic PAH
- Community outreach, education, & dissemination
This Project will evaluate the toxicity of selected alkylated and oxygenated PAH, and PAH extracts from seafood (in collaboration with Project 2) using validated cell-based assay systems, as well as elucidate the metabolism of thepetrogenic PAH. The project will also examine the potential for the petrogenic PAH to cause oxidative stress and DNAmutagenesis.