The Newsroom    Published Tuesday, Oct. 10, 2006, 10:53 AM
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Colon Cancer: Enzyme may be key

The Jackson (Miss.) Clarion-Ledger, Oct. 10, 2006http://www.clarionledger.com/apps/pbcs.dll/article?AID=/20061010/HEALTH/610100304/1242/health Texas researchers have determined that stopping the activity of a single enzyme could shut down the toxic network of biochemical signals that promotes colon cancer cell growth.  In cell culture experiments, scientists from the University of Texas Medical Branch at Galveston and the University of Texas at Arlington showed that blocking the production of aldose reductase halted the growth of human colon cancer cells implanted in laboratory mice. A paper about the discovery was published Oct. 1 in the journal Cancer Research.



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