The Newsroom    Published Friday, Sep. 24, 2010, 10:06 AM
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Pharmaceutical forefront

Medical Journal – Houston, September 1, 2010 - (Link unavailable)

UTMB researchers believe they’ve found a way to use widely available blood pressure drugs to fight the muscular weakness that normally accompanies aging. The discovery draws on research linking the loss of muscle mass with age-related changes in the behavior of the hair-thin blood vessels, or capillaries, which supply muscles with the amino acids they need for growth. Drugs that induce blood vessels to widen, called vasodilators, are commonly used to control high blood pressure and prevent angina. The UTMB study used sodium nitroprusside, a drug used in hospitals and administered intravenously. By giving a group of healthy older volunteers a vasodilator, “we were able to make our 70-year-olds look like 30-year-olds, at least in terms of muscle growth,” said postdoctoral fellow Kyle Timmerman, a lead author of the study. The study was co-led by medical student and graduate research fellow Jessica Lee. (Link unavailable.)

 




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