Office of Strategic Research Development

R01

Supports a discrete, specified, circumscribed research project. Encourages new, exploratory and developmental research projects by providing support for the early stages of project development. Sometimes used for pilot and feasibility studies.

• NIAID Examples
• Behavioral Research Examples
• Cancer Epidemiology Examples
• Implementation Science Examples
• NIDCD Examples

R03

Provides limited funding for a short period of time to support a variety of types of projects, including pilot or feasibility studies, collection of preliminary data, secondary analysis of existing data, small, self-contained research projects, development of new research technology, etc.

• Cancer Epidemiology Examples
• NIAID Examples

R15

Supports small research projects in the biomedical and behavioral sciences conducted by undergraduate and/or graduate students and faculty in institutions of higher education that have not been major recipients of NIH research grant funds.

• NIAID Examples

R21/R33

Provides a second phase for the support for innovative exploratory and development research activities initiated under the R21 mechanism. Although only R21 awardees are generally eligible to apply for R33 support, specific program initiatives may establish eligibility criteria under which applications could be accepted from applicants demonstrating progress equivalent to that expected under R33.

• NIAID Examples

R37

To provide long-term grant support to investigators whose research competence and productivity are distinctly superior and who are highly likely to continue to perform in an outstanding manner. Investigators may not apply for a MERIT award. Program staff and/or members of the cognizant National Advisory Council/Board will identify candidates for the MERIT award during the course of review of competing research grant applications prepared and submitted in accordance with regular PHS requirements.

• Implementation Science Examples

R41-Small Business Technology Transfer (STTR) Grants - Phase I

To support cooperative R&D projects between small business concerns and research institutions, limited in time and amount, to establish the technical merit and feasibility of ideas that have potential for commercialization. Awards are made to small business concerns only.

• NIAID Examples

R42-Small Business Technology Transfer (STTR) Grants - Phase II

To support in - depth development of cooperative R&D projects between small business concerns and research institutions, limited in time and amount, whose feasibility has been established in Phase I and that have potential for commercialization. Awards are made to small business concerns only.

• NIAID Examples
• NIA Examples 

R43-Small Business Innovation Research Grants (SBIR) - Phase I

To support projects, limited in time and amount, to establish the technical merit and feasibility of R&D ideas which may ultimately lead to a commercial product(s) or service(s).

• NIAID Examples
• NIA Examples 

R44-Small Business Innovation Research Grants (SBIR) - Phase II

To support in - depth development of R&D ideas whose feasibility has been established in Phase I and which are likely to result in commercial products or services. SBIR Phase II are considered “Fast-Track” and do not require National Council Review.

• NIAID Examples
• NIA Examples 

K01-Research Scientist Development Award - Research & Training

For support of a scientist, committed to research, in need of both advanced research training and additional experience.

• NIAID Examples

K08-Clinical Investigator Award (CIA)

To provide the opportunity for promising medical scientists with demonstrated aptitude to develop into independent investigators, or for faculty members to pursue research aspects of categorical areas applicable to the awarding unit, and aid in filling the academic faculty gap in these shortage areas within health profession's institutions of the country.

• NIAID Examples

F32-Postdoctoral Individual National Research Service Award

To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in specified health-related areas.

• NIAID Examples

K99-Career Transition Award

To support the initial phase of a Career/Research Transition award program that provides 1-2 years of mentored support for highly motivated, advanced postdoctoral research scientists.

• NIA Examples

U01-Research Project--Cooperative Agreements

To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

• NIAID Examples