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Frederick A. Murphy, DVM, PhD
Professor Emeritus
University of Texas Medical Branch
Galveston, TX 77555 USA
Mailing address:
8300 Burdette Road Unit B661
Bethesda, MD 20817
Cell: (409) 739-3332
Tel: (301) 968-4798


eBook, Foundations of Virology, 2nd Edition, 2024.

(This is a very large file and takes some time to download.)

This revision has the usual additions and updating of text and images, but also has a new 10-page section on SARS-CoV-2/COVID written by Kay Holmes. It has been revised up to January of 2024, now with 630 pages and still with >2,000 images. As always, this is still a history of virology centered on discoverers and discoveries, inventors and inventions, and developers and technologies, with particular emphasis on the seminal initial discoveries that have become the foundation of today’s science. Now this extends to the ongoing pandemic virus / disease, SARS-CoV2 / COVID, with a section that will need ongoing updating by Kay Holmes – but we shall deal with this mañana. The book still has a massive table of contents that serves as a rather comprehensive timeline; it is indexed and has a suggested additional reading list. The images are included at the highest resolution possible for online sharing, still best viewed on a large high-res monitor.

Detail of the following pages.

(1) The Virus Images: Electron Micrographs link leads to 22 virus images (plus various colorized versions of some of the images). The images and all the other resources in this website may be reprinted and/or used for educational or non-profit purposes, as long as they are credited appropriately. Note: large .tif or .jpg images will be downloaded when you right-click on the thumbnails or choose "Save Image as..." or "Save Picture as..." according to your browser. The large images range from 5 to 10 Mb.

(2) The Foundations of Virology link leads to the main (combined) PowerPoint slide set, Foundations of Virology, and to the same set broken into six smaller files. This tab also contains the file for my 618 page eBook, with the same title, Foundations of Virology. This is a 300Mb .pdf file, which takes about 6 minutes to download on my home computer, but it is the lowest resolution (smallest file) that still yields high quality images. The highest resolution file (1Gb), suitable for printing, is also available, but I would have to send it via Dropbox.

(3) The Virology Papers tab contains a Word file (.docx), Discovers and Discoveries, which has a large chronological table matching the entries in the PowerPoint slide set and the eBook. This tab also contains .pdf files of several of my old papers that are not available on the Internet.

(4) This Week in Virology – TWiV #625: entitled "Fred Murphy, Virologist For All Seasons." This is a link to an interview by Vincent Racaniello and Richard Condit on 27 February 2020 (before masks, the last interview before COVID 19 / SARS-CoV-2 came to occupy all TWiV sessions). “Vincent and Rich visit Fred Murphy to hear about his wide-ranging career in virology, spanning many institutions, involving dangerous viruses like rabies virus, Ebola virus (he took that famous iconic image), Marburg virus, Lassa virus, coronaviruses, and later writing a history of the field.”

(5) Foundation Images for the Study of the History of Yellow Fever – PowerPoint and PDF files of a large set of images of the history of yellow fever, from the Philadelphia epidemic of 1793, through the many epidemics of the 19th century, to the discovery of the virus and its mode of transmission, to the dramatic influence of the virus/disease on the building of the Panama Canal, to the elimination of urban yellow fever worldwide, to the development of the 17-D vaccine. Any/all of the images are in the public domain and are available for any educational purpose, from school presentations and papers to scholarly seminars and reviews.