Dr. Agenor Limon's Lab Publications

Selected Publications

  • Ordaz RP, Garay E, Limon A, Pérez-Samartín A, Sánchez-Gómez MV, Robles-Martínez L, Cisneros-Mejorado A, Matute C, Arellano RO. GABAA Receptors Expressed in Oligodendrocytes Cultured from the Neonatal Rat Contain α3 and γ1 Subunits and Present Differential Functional and Pharmacological Properties. Mol Pharmacol. 2021 Feb;99(2):133-146.

  • Limon A, Hagopian G, Reyes-Ruiz JM, Miledi R. Tonic Calcium-Activated Chloride Current Sustained by ATP Release and Highly Desensitizing Human P2X1 Receptors. Neuroscience. 2020 Jul 15;439:332-341.

  • Shen K, Zeppillo T, Limon A. Regional transcriptome analysis of AMPA and GABAA receptor subunit expression generates E/I signatures of the human brain. Sci Rep. 2020 Jul 9;10(1):11352.

  • Zeppillo T, Schulmann A, Macciardi F, Hjelm BE, Föcking M, Sequeira PA, Guella I, Cotter D, Bunney WE, Limon A, Vawter MP. Functional impairment of cortical AMPA receptors in schizophrenia. Schizophr Res. 2020 Jun 5, in Press.

  • Scaduto P, Sequeira A, Vawter MP, Bunney W, Limon A. Preservation of global synaptic excitatory to inhibitory ratio during long postmortem intervals. Sci Rep. 2020 May 25;10(1):8626. 

  • Singh A, Allen D, Fracassi A, Tumurbaatar B, Natarajan C, Scaduto P, Woltjer R, Kayed R, Limon A, Krishnan B, Taglialatela G. Functional Integrity of Synapses in the Central Nervous System of Cognitively Intact Individuals with High Alzheimer's Disease Neuropathology Is Associated with Absence of Synaptic Tau Oligomers. J Alzheimers Dis. 2020;78(4):1661-1678. 

  • Limon A, Delbruck E, Yassine A, Pandya D, Myers RM, Barchas JD, Lee F, Schatzberg, Watson SJ, Akil H, Bunney WE, Vawter MP, Sequeira A. Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABAA receptors. Transl Psychiatry. 2019 Sep 5;9(1):218. 

  • Sequeira A, Shen K, Gottlieb A, Limon A. Human brain transcriptome analysis finds region- and subject-specific expression signatures of GABAAR subunits. Commun Biol. 2019;2:153. 

  • Baglietto-Vargas D, Prieto GA, Limon A, Forner S, Rodriguez-Ortiz CJ, Ikemura K, Ager RR, Medeiros R, Trujillo-Estrada L, Martini AC, Kitazawa M, Davila JC, Cotman CW, Gutierrez A, LaFerla FM. Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. Aging Cell. 2018 Aug;17(4):e12791.

  • Limon A, Mamdani F, Hjelm BE, Vawter MP, Sequeira A. Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission. Neurosci Biobehav Rev. 2016 Jul;66:80-91.

  • Limon A, Estrada-Mondragón A, Ruiz JM, Miledi R. Dipicrylamine Modulates GABAρ1 Receptors through Interactions with Residues in the TM4 and Cys-Loop Domains. Mol Pharmacol. 2016 Apr;89(4):446-56. 

  • Limon A, Reyes-Ruiz JM, Miledi R. Loss of functional GABA(A) receptors in the Alzheimer diseased brain. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10071-6. doi: 10.1073/pnas.1204606109. Epub 2012 Jun 12. PubMed PMID: 22691495; PubMed Central PMCID: PMC3382476.

  • Ochoa-de la Paz LD, Estrada-Mondragón A, Limón A, Miledi R, Martínez-Torres A. Dopamine and serotonin modulate human GABAρ1 receptors expressed in Xenopus laevis oocytes. ACS Chem Neurosci. 2012 Feb 15;3(2):96-104.

  • Limon A, Reyes-Ruiz JM, Vaswani RG, Chamberlin AR, Miledi R. Kaitocephalin antagonism of glutamate receptors expressed in Xenopus oocytes. ACS Chem Neurosci. 2010 Mar 17;1(3):175-181.

  • Limon A, Reyes-Ruiz JM, Miledi R. Microtransplantation of neurotransmitter receptors from postmortem autistic brains to Xenopus oocytes. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10973-7. doi: 10.1073/pnas.0804386105. Epub 2008 Jul 21. PubMed PMID: 18645182; PubMed Central PMCID: PMC2504813.

  • Limon A, Reyes-Ruiz JM, Eusebi F, Miledi R. Properties of GluR3 receptors tagged with GFP at the amino or carboxyl terminus. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15526-30. doi: 10.1073/pnas.0706773104. Epub 2007 Sep 19. PubMed PMID: 17881566; PubMed Central PMCID: PMC2000508.

  • Limon A, Pérez C, Vega R, Soto E. Ca2+-activated K+-current density is correlated with soma size in rat vestibular-afferent neurons in culture. J Neurophysiol. 2005 Dec;94(6):3751-61.