Publications

Scaduto P, Lauterborn JC, Cox CD, Fracassi A, Zeppillo T, Gutierrez TA, Keen CD, Crane PK, Mukherjee S, Russell WK, Taglialatela G, Limon A (2023): Functional excitatory to inhibitory imbalance and loss of cognitive performance in people with Alzheimer’s Disease neuropathologic changes. Acta Neuropathol 145(3):303-324.
Fracassi A, Marcatti M, Tumurbaatar, B, Woltjer R, Moreno S, Taglialatela G (2023): TREM2-induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology. Brain Pathol, 33(1):e13108
Walker JM, Kazempour Dekhordi S, Fracassi A, Vanschoiack A, Pavenko A, Taglialatela G, Woltjer R, Richardson TE, Zare H, Orr ME (2022): Differential protein expression in the hippocampi of resilient individuals identified by digital spatial profiling. Acta Neuropathol Commun 10(1):23
Marcatti M, Fracassi A, Montalbano M, Natarajan C, Krishnan B, Kayed R, Taglialatela G (2022): Interplay between amyloid beta and tau oligomers at human synapses may suggest shifting targets towards effective AD therapies. Cell Mol Life Sci. Apr. 4;79(4):2222. Doi:10.1007/s00018-022-04255-
Saieva S, Taglialatela G (2022): Near-Infrared Light Reduces Glia Activation and Modulates Neuroinflammation in Brains of Diet Induced Obese Mice. Sci Rep, Jun 27;12(1):10848. Doi:10.108/s41598-022-14812-8
Freberg E, Taglialatela G (2022). Exercise as a potential therapeutic strategy to target the clinical link between depression and Alzheimer's Disease. J Alzheimer Dis, Aug 29. DOI: 10.3233/JAD-210632
Nazari HK, Karimaghei C, van der Merwe, R Monatalbano M, Taglilatela G, Vargas G, Zhang W, Matamedi M (2022). Age dependence of retinal vascular plexus attenuation in the triple transgenic mouse of Alzheimer's disease. Exp Eye Res. 10.1016/j.exer.2021.108879. Epub 2021 Dec 10. PMID: 34896306.
Singh A, Allen D, Fracassi A, Tumurbaatar B, Natarajan C, Scaduto P, Woltjer R, Kayed R, Limon A, Krishnan B, Taglialatela G (2020). Functional integrity of synapses in the central nervous system of cognitively intact individuals with high Alzheimer’s neuropathology is associated with absence of synaptic tau oligomers. J Alzheimers Dis, in press.
Fracassi A, Marcatti M, Zolochevska O, Tabor N, Woltjer R, Moreno S, Taglialatela G (2020). Oxidative damage and antioxidant response in frontal cortex of demented and non-demented individuals with Alzheimer's neuropathology. J Neurosci, in press.
Zolochevska O, Taglialatela G (2020). Selected microRNAs Increase Synaptic Resilience to the Damaging Binding of the Alzheimer's Disease Amyloid Beta Oligomers. Mol Neurobiol. 57(5):2232-2243.
Krishnan B, Sallam HS, Tumurbataar B, Saieva S, Baymon D, Tuvdendorj D, Micci MA, Abate N, Taglialatela G (2020). Amelioration of hippocampal dysfunction by adipose tissue-targeted stem cell transplantation in a mouse model of type 2 diabetes. J Neurochem. 153(1):51-62.
Micci MA, Krishnan B, Bishop E, Zhang WR, Guptarak J, Grant A, Zolochevska O, Tumurbaatar B, Franklin W, Marino C, Widen SG, Luthra A, Kernie SG, Taglialatela G (2019). Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes. Mol Neurodegener. 14(1):25.
Comerota MM, Tumurbaatar B, Krishnan B, Kayed R, Taglialatela G (2019). Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies. Mol Neurobiol. 56(5):3341-3355.
Marino C, Krishnan B, Cappello F, Taglialatela G (2019). Hsp60 Protects against Amyloid β Oligomer Synaptic Toxicity via Modification of Toxic Oligomer Conformation. ACS Chem Neurosci. 10(6):2858-2867.
Franklin W, Krishnan B, Taglialatela G (2019). Chronic synaptic insulin resistance after traumatic brain injury abolishes insulin protection from amyloid beta and tau oligomer-induced synaptic dysfunction. Sci Rep. 9(1):8228.
Zolochevska O, Bjorklund N, Woltjer R, Wiktorowicz JE, Taglialatela G (2018). Postsynaptic Proteome of Non-Demented Individuals with Alzheimer's Disease Neuropathology. J Alzheimers Dis. 65(2):659-682.
Comerota MM, Krishnan B, Taglialatela G (2017). Near infrared light decreases synaptic vulnerability to amyloid beta oligomers. Sci Rep. 7(1):15012.
Briley D, Ghirardi V, Woltjer R, Renck A, Zolochevska O, Taglialatela G, Micci MA (2016). Preserved neurogenesis in non-demented individuals with AD neuropathology. Sci Rep. 6:27812.
Franklin W, Taglialatela G (2016). A method to determine insulin responsiveness in synaptosomes isolated from frozen brain tissue. J Neurosci Methods. 261:128-34.
Bjorklund NL, Reese LC, Sadagoparamanujam VM, Ghirardi V, Woltjer RL, Taglialatela G (2012). Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer's disease neuropathology. Mol Neurodegener. 7:23.
Reese LC, Laezza F, Woltjer R, Taglialatela G (2011). Dysregulated phosphorylation of Ca(2+) /calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer's disease. J Neurochem. 119(4):791-804.
Reese LC, Zhang W, Dineley KT, Kayed R, Taglialatela G (2008). Selective induction of calcineurin activity and signaling by oligomeric amyloid beta. Aging Cell. 7(6):824-35.