Seminal Publications

• Puangmalai N, Bhatt N, Puangmalai N, Bhatt N, Montalbano M, Sengupta U, Gaikwad S, Ventura  F, McAllen S, Ellsworth A, Garcia S, and Kayed R. Internalization mechanisms of brain-derived Tau oligomers from patients with Alzheimer’s disease, Progressive Supranuclear Palsy and Dementia with Lewy Bodies. Cell Death and Disease. 2020, 11 (5), 1-16. PMID: 32366836
• Mauro Montalbano, Salome McAllen, Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, Omar D. Johnson, Michael G. Kharas, Rakez Kayed. RNA-Binding Proteins Musashi and Tau soluble aggregates initiate nuclear dysfunction in tauopathies. Nature Comunications. 2020. Published.
• Gerson JE, Gerson JE, Farmer K, Henson N, Castillo-Carranza DL, Carretero-Murillo M, Sengupta U, Barrett A, Kayed R. Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy. 2018 Feb, Molecular Neurodegeneration. 2018 Mar 15;13(1):13. PMID: 29544548. PMCID: PMC5856311.
• Castillo-Carranza DL, Gerson JE, Sengupta U, M. J. Guerrero-Muñoz MJ,  Lasagna-Reeves CA,  Kayed R. (2014). Passive immunization with tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary. Journal of Neuroscience, Mar 19; 34(12):4260-72. PMID: 24647946.
• Lasagna-Reeves CA, Castillo-Carranza DL, Guerrero-Munoz MJ, Jackson GR, Kayed R. (2010). Preparation and characterization of neurotoxic tau oligomers. Biochemistry, Nov 30; 49(47):10039-41. Rapid reports. PMID: 21047142.
• Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Clos AL, Jackson GR, Kayed R. (2011). Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. Molecular Neurodegeneration, Jun 6; 6:39. PMCID: PMC3224595
• Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Sarmiento J, Troncoso J, Jackson GR, Kayed R. (2012). Identification of oligomers at early stages of tau aggregation in Alzheimer's disease. FASEB J., 26 (5):1946-59. PMCID: PMC4046102
• Lasagna-Reeves, CA, Castillo-Carranza DL, Sengupta U, Guerrero-Munoz MJ, Kiritoshi T, Neugebauer V, Jackson GR, Kayed R. (2012). Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau. Scientific Reports, Oct 3; 2:700. PMCID: PMC463004.
• Castillo-Carranza DL, Guerrero-Munoz MJ, Gerson J, Sengupta U, Kayed R. α-Synuclein oligomers induce a unique toxic tau strain. Biological Psychiatry. 2018 Jan 17.  2018 Oct 1;84(7):499-508.PMID: 29478699. Chosen for cover.
• Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG. (2003). Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science, Apr 18; 300 (5618):486-9. PMID: 12702875