Your child has a fever, cough and headache. You reach in the medicine cabinet and find several bottles of pills and liquid medicine. Brand names vary, but the generic names include ibuprofen, acetaminophen, naproxen and aspirin. How do you know what is right for your child’s discomfort? Is there any difference?

The answer depends on your child’s age, weight and symptoms. If you are not sure which medicine to give your child, check with your pediatrician or heath care provider according to the American Academy of Pediatrics.

Two main kinds of pain relievers are available for most children without prescription: acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs). There are many brands of these two pain relievers/fever reducers. Most can be found in the children’s section of your drugstore. Adult pain relievers and fever reducers contain higher amounts of medicine and should be used only for the ages listed on the package.

• Acetaminophen (Tylenol) is effective for infants and children of all ages. However, the American Academy of Pediatrics advises families to call their pediatrician if their infant 3 months and younger has a rectal temperature over 101 degrees Fahrenheit. Recently, the Food and Drug Administration advised people to watch for rare — but serious skin reactions — in children who take acetaminophen.

• NSAIDs include ibuprofen (Advil, Motrin), naproxen (Naprelan, Naprosyn, Aleve and Anaprox) and aspirin (Bayer, St. Joseph, Bufferin).

• Ibuprofen is safe for children ages 6 months and older

• Naproxen is not used to treat fever in children and infants

• Aspirin is not recommended for children who are recovering from the flu or chickenpox because it can cause a rare but serious brain disorder called Reye syndrome. The Academy of Pediatrics recommends that parents use acetaminophen or ibuprofen, not aspirin.

Parents should always read the label before giving medicine to their child to make sure they are not combining two different kinds of medicine incorrectly or giving double the dose of medicine such as a cold medicine that includes a pain reliever.

Always follow the age, weight and dosing recommendations listed on the medicine label. Some medicines should never be given to infants and young children. Some are for children ages 6 and older, and some are only for children 12 and older.

Medicine cups or syringes and dosing instructions are listed in milliliters (mL). Never use a kitchen spoon to measure medicine. It can lead to an overdose.

Sally Robinson is a clinical professor of pediatrics at UTMB Children’s Hospital. This column isn’t intended to replace the advice of your child’s physician.