 | LaCrosse virus infection in mouse brain. This is an ultra-thin section of the brain of a mouse infected with La Crosse virus (family Bunyaviridae, genus Bunyavirus) at six days post-infection when the mouse was moribund. Virions (100nm in diameter) are accumulating within intracytoplasmic (Golgi) vesicles as a result of budding. Magnification approximately x40,000 (composite). Micrograph from F. A. Murphy, University of Texas Medical Branch, Galveston, Texas. Download TIF |
 | La Crosse virus, purified from an infected Vero cell culture. Virions have been penetrated by the negative contrast stain; the fine surface projections and envelope (derived from Golgi membrane of the infected cell) that are characteristic of viruses like this (family Bunyaviridae, genus Bunyavirus) are clear, but viral nucleocapsids, which are very fine strands, are not. Magnification: approximately x80,000.
Micrograph from F. A. Murphy, University of Texas Medical Branch, Galveston, Texas. Download TIF |