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Jia ZhouThe Newsroom


UTMB's Dr. Jia Zhou has been named a Fellow of the National Academy of Inventors! This is the highest professional distinction accorded to academic inventors.

Dr. Zhou is a Professor in our Department of Pharmacology & Toxicology. He is also a member of the Center for Addiction Research, the Center for Biodefense and Emerging Infectious Diseases, and the Sealy Center for Molecular Medicine. Congratulations to our Dr. Zhou on this outstanding achievement.

2020 Awards

Amanda Price - 2020 George Sealy Research Award in Neurology

Erik Garcia, PhD - 2020 CPDD Early Career Travel Award

Dennis Sholler - 2020 CPDD Early Career Investigators Travel Award

Christina Merritt - 2020 CPDD Travel Award

Ashley Nilson - 2020 ASPET General Travel Award

Eric Wold - 2020 Innovations to Impact at Yale Awardee


Ezeomah, C., Cunningham, K.A., Stutz, S.J., Fox, R.G., Bukreyeva, N., Dineley, K.T., Paessler, S. and Cisneros, I.E. Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats. Brain Behav. Immun. 2020 Mar 9;S0889-1591(19)31433-3. PMID:32165150 Online ahead of print.

Wang, P., Luchowska-Stańska, U., Chen, H., Liu, Z., Wiejak, J., Whelan, P., Morgan, D., Lochhead, E., Barker, G., Rehmann, H., Yarwood, S.J., and Zhou, J. Synthesis and biochemical evaluation of non-cyclic nucleotide exchange protein directly activated by cAMP1 (EPAC1) regulators. J. Med. Chem. In Press. doi: 10.1021/acs.jmedchem.9b02094, 2020. PMID: 32340447

Liu, Z., Chen, H., Wang, P., Li, Y., Wold, E.A., Leonard, P.G., Joseph, S., Brasier, A.R., Tian, B., and Zhou, J. Discovery of orally bioavailable chromone derivatives as potent and selective BRD4 inhibitors: Scaffolding hopping, optimization and pharmacological evaluation. J. Med. Chem., 63 (10), 5242-5256, 2020. PMID: 32255647. PMCID: In progress [Journal Cover Article]

Price, A.E., Stutz, S.J., Hommel, J.D., Anastasio, N.C., and Cunningham, K.A. Anterior insula regulation of high fat food binge intake and cue reactivity in male rats. Appetite 133: 231-239, 2019. PMCID: PMC6594399

Anastasio, N.C., Stutz, S.J., Price, A.E., Davis-Reyes, B.D., Sholler, D.J., Ferguson, S.M., Neumaier, J.F., Moeller, F.G., Hommel, J.D., and Cunningham, K.A. Convergent neural connectivity in motor impulsivity and high-fat food binge-like eating in male Sprague-Dawley rats. Neuropsychopharmacology 44:1752-1762, 2019. PMCID: PMC6785029 (available 9/1/20)

Wold, E.A., Chen, J., Cunningham, K.A., and Zhou, J. Allosteric modulation of class A GPCRs: Targets, agents, and emerging concepts. J Med. Chem. 62:88-127, 2019. PMCID: PMC6556150

Ma, L., Steinberg, J.L., Bjork, J.M., Taylor, B.A., Arias, A.J., Anastasio, N.C., Zuniga, E.A., Lennon, M., Cunningham, K.A., and Moeller, F.G., Cingulo-hippocampal effective connectivity positively correlates with drug-cue attentional bias in opioid use disorder. Psychiatry Research: Neuroimaging 294:110977, 2019 PMID: 31439409 (PMCID: In Process)

McCue, D.M., Kasper, J.M., 13, A., and Hommel, J.D. Incubation of feeding behavior is regulated by neuromedin U receptor 2 in the paraventricular nucleus of the hypothalamus. Behavioural Brain Research, S0166-4328(18)30580-1, 2019. PMCID: PMC6309744

Price, A.E., Sholler, D.J., Stutz, S.J., Anastasio, N.C., and Cunningham, K.A. Endogenous serotonin 5-HT2A and 5-HT2C receptors associate in the medial prefrontal cortex. ACS Chemical Neuroscience 10(7):3241-3248, 2019. PMCID: PMC6640104

Davis-Reyes, B.D., Campbell, V.M., Land, M.A., Chapman, H.L., Stafford, S.J., and Anastasio, N.C. Profile of cortical N-methyl-D-aspartate receptor subunit expression associates with inherent motor impulsivity in rats. Biochemical Pharmacology 168:204-213, 2019. PMCID: PMC6733662 (available 10/1/20)

Ye, N., Li, B., Mao, Q., Wold, E.A., Tian, S., Allen, J.A., and Zhou, J. Orphan receptor GPR88 as an emerging neurotherapeutic target. ACS Chem. Neurosci 10 (1), 190-200, 2019. PMCID: PMC6548324

Wang, P., Felsing, D. E., Chen, H., Raval S.R., Allen J.A., and Zhou, J. Synthesis and pharmacological evaluation of non-catechol G protein biased and unbiased dopamine D1 receptor agonists. ACS Med. Chem. Lett 10 (5), 792-799, 2019. PMCID: PMC6511950. [Journal Cover Article; F1000Prime Recommended Article]

WTian, B., Hosoki, K., Liu, Z., Yang, J., Zhao, Y., Sun, H., Zhou, J., Rytting, E., Kaphalia, L., Calhoun, W.J., Sur, S., and Brasier, A.R. Mucosal bromodomain-containing protein 4 (BRD4) mediates aeroallergen-induced inflammation and remodling. J. Allergy Clin. Immunol., 143 (4), 1380-1394, 2019. PMCID: PMC6490683ild, C.T., Miszkiel, J.M., Wold, E.A., Soto, C.A., Ding, C., Hartley, R.M., White, M.A., Anastasio, N.C., Cunningham, K.A., and Zhou, J. Design, synthesis and characterization of 4-undecylpiperidine-2-carboxamides as positive allosteric modulators of the serotonin (5-HT) 5-HT2C receptor. J. Med. Chem. 62 (1), 288-305, 2019. PMCID: PMC6533912

Xu, J., Xie, X., Ye, N., Zou, J., Chen, H., White, M.A., Shi, P.Y., and Zhou, J. Design, synthesis, and biological evaluation of substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5-b]pyridine-7,3'-indoline]-2',5(3H)-dione analogues as potent NS4B inhibitors for the treatment of dengue virus infection. J. Med. Chem., 62 (17), 7941-7960, 2019. PMID: 31403780. PMCID: In progress

Niu, Q., Liu, Z., Liu, F., Alamer, E., Fan, X., Chen, H., Endsley, J., Gelman, B.B., Tian, B., Kim, J.H., Michael, N.L., Robb, M.L., Ananworanich, J., Zhou, J.* (Co-corresponding author), and Hu, H*. Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV. J. Clin. Investig. (JCI), 129 (8), 3361-3373, 2019. PMCID: PMC6668673




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