research in the Center for Biodefense and Emerging Infectious Diseases (CBEID) addresses pathogens of medical importance that cause tropical and emerging infectious diseases. Many of these bacterial pathogens have the potential to be used as biological
weapons and are therefore categorized by federal law as select agents .
They are also listed on NIAID's Category A, B, and C pathogens list
The bacterial pathogens studied at the CBEID can be divided into vector-borne and non vector-borne. Some of the agents under study infect wild and domestic animals and are responsible for emerging human zoonoses.
Areas of Bacterial Research
1. Arthropod-borne bacterial agents
Lucas Blanton, Donald Bouyer, Rong Fang, Bin Gong, Jere McBride, Juan Olano, Seva Popov, Lynn Soong, David Walker, Xuejie Yu
Ashok Chopra, Vladimir Motin, Tonia Eaves-Pyles
2. Non-vector-borne bacterial agents
3. Bacterial pathogenesis
Ashok Chopra, Janice Endsley, Bin Gong, Jere McBride, Vladimir Motin, Juan Olano, Johnny Peterson, Vsevolod Popov, Alfredo Torres, David Walker
4. Protective immune mechanisms
Yingzi Cong, Rong Fang, Jere McBride, Victor Reyes, Tonyia Eaves-Pyles, Lynn Soong, David Walker
5. Antimicrobial activity
Janice Endsley, Vladimir Motin, Johnny Peterson, Alfredo Torres, Jia Zhou
Many of the bacterial pathogens under study in the CBEID require
biosafety level 3 containment because these infectious agents may cause
serious or potentially lethal diseases as a result of exposure by the
inhalation route. Facilities for research on these agents is available
in the Galveston National Laboratory
the Keiller Building. Training of graduate students and fellows is
supported by NIH T32 training programs and the McLaughlin endowment.
Vaccine development is fostered by the UTMB Sealy Center for Vaccine Development
The Sealy Center for Molecular Medicine
and the Sealy Center for Structural Biology and Molecular Biophysics
provide bioinformatics, genomics, and microarray support.