Your Grandmothers Diet Could affect your Child's Health

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Maternal gut microbiota mediate intergenerational effects of high-fat diet on descendant social behavior
Dysbiosis of the maternal gut microbiome during pregnancy is associated with adverse neurodevelopmental outcomes. We previously showed that maternal high-fat diet (MHFD) in mice induces gut dysbiosis, social dysfunction, and underlying synaptic plasticity deficits in male offspring (F1). Here, we reason that, if HFD mediated changes in maternal gut microbiota drive offspring social deficits, then MHFD-induced dysbiosis in F1 female MHFD offspring would likewise impair F2 social behavior...

Study Finds Grandmaternal High-fat Diet can Impair Social Behavior in Descendants
New research from investigators at the University of Texas Medical Branch finds that adverse effects of maternal high-fat diet on brain development and related disorders, including autism spectrum disorder, could carry over to a second generation of descendants. In essence, grandmaternal diets could impact brain development and behavior in their grandchildren...