Medical Discovery NewsBridging the World of Medical Discovery and You

Recent Episodes

Dementia Clues In Your Voice

MP3 WAV

  • Dementia is a major health issue in America. Everyone likely knows of a family member, a neighbor or a friend who has or had dementia. It is likely to become even more of a concern as people live longer and the population ages. Diagnosis at the early stages can be challenging, and we need new approaches for early intervention. Especially with a disease as devastating as this, quality of life for patients is important. Biomedical technology to the rescue! Researchers have developed a machine learning model that can identify mild cognitive impairment in voice recordings.

    For this study, the scientists evaluated voice recordings from neuropsychological tests from more than 1,000 people. The results were remarkable, with 88% accuracy in distinguishing normal cognition from mild dementia and 92% accuracy in identifying normal cognition from more advanced dementia. That is impressive and could represent a real breakthrough.

    The approach involved using natural language processing to transcribe the audio recordings to written text. This technology is similar to the voice-to-text capabilities your smartphone has, but the system the scientists used was more sophisticated. The scientists then trained an AI process to identify signs of cognitive impairment, and processed the text through it. The results showed that one particular portion of the neuropsychological test was useful in accurately diagnosing dementia. That section of the test was an exercise where patients were asked to describe a picture with one word. Scientists want to further improve the tests to bring the numbers up even higher.

    A previous study in Japan used speaking rate and pause intervals (pauses to find the right word) as a marker for Alzheimer's. That study resulted in a 90% accuracy in identification of Alzheimer's patients based on telephone audio files from more than 100 patients. This new study focused not on the way patients were speaking, but what they said.eople without fear of infection. Those who continue to shed virus beyond this time are at risk for more severe issues.

    Scientists also thought that following voice patterns of an individual over time would help in identifying these subtle changes in cognitive function. This development of a diagnostic biomarker based on analysis of a person's voice could improve early diagnosis and help people who may develop this devastating disease.

    So how far away are we from assessing cognitive decline by telehealth or a virtual visit? One day, you could have a conversation with your doctor or a nurse, read some text or respond to a few questions. Your voice is analyzed and a score is generated for your medical file documenting your cognitive decline or not! Of course, if there are concerns, there would likely be a follow-up with your physician.

    This is becoming a major health issue in the U.S. as 6.5 million people have been diagnosed with Alzheimer's. Another estimated 5 million are living with mild cognitive impairment. These numbers will continue to rise as our population ages. Early diagnosis and intervention can slow the disease to improve people's quality of life.

More Information

Detection of dementia on voice recordings using deep learning: a Framingham Heart Study
Identification of reliable, affordable, and easy-to-use strategies for detection of dementia is sorely needed. Digital technologies, such as individual voice recordings, offer an attractive modality to assess cognition but methods that could automatically analyze such data are not readily available...

AI Detects Dementia in Voice Recordings
There are over 10 million new cases of dementia each year worldwide, according to the World Health Organization. Researchers conduct neuropsychological tests to assess patients' cognitive functioning, but transcribing the audio recordings takes a lot of time. Artificial intelligence (AI) algorithms can be used to analyze voice recordings of individuals to detect their dementia status efficiently and accurately...

Two individuals wearing headphones stand in a recording booth, speaking into microphones with a music stand holding printed pages between them.

 Medicine...

Medicine is constantly advancing – that is a great thing about life in the 21st century. But it doesn’t just happen. Dedicated biomedical scientists are making discoveries that translate into those new medical advances.

Biomedical science is broad, encompassing everything from social science to microbiology, biochemistry, epidemiology, to structural biology and bioinformatics to name just a few areas. And, it can involve basic fundamental biology, the use of AI and chemistry to clinical studies that evaluate new medicines in patients.

No matter the research focus, the goal is always the same, to advance human health. It may take a few months, a few years or for fundamental science, a few decades. Few people make the connection that biomedical science is medicine and that biomedical scientists are working today on the medicine of tomorrow. Our weekly 500-word newspaper columns and 2-minute radio shows and podcasts provide insights into a broad range of biomedical science topics.

Medical Discovery News is dedicated to explaining discoveries in biomedical research and their promise for the future of medicine.

Podcasts

Alternatively, you can copy and paste the following web address (URL) into iTunes as a new subscription:
https://www.medicaldiscoverynews.com/shows/audio/mdnews.rss

You can also search and subscribe to "Medical Discovery News" in the podcast section of iTunes.

The www.medicaldiscoverynews.com web site and Medical Discovery News radio program (Program) are made possible by The University of Texas Medical Branch at Galveston (UTMB)as a community service and are intended to advance UTMB's mission of providing scholarly teaching, innovative scientific investigation, and state-of-the-art patient care in a learning environment to better the health of society and its commitment to the discovery of new innovative biomedical and health services knowledge leading to increasingly effective and accessible health care for the citizens of Texas.

All information provided on the web site and in the Program is for informational purposes only and is not intended for use as diagnosis or treatment of a health problem or as a substitute for consulting a licensed medical professional. Any information obtained by participating as a web site visitor or program listener is not intended to and should not be considered to constitute medical advice.

Thoughts and opinions expressed on the Program or on the website are those of the authors or guests and do not necessarily reflect the opinions of UTMB. The provision of links to other websites is not to be construed as written or implied sponsorship or endorsement of such websites by UTMB.

Please contact Dr. David Niesel or Dr. Norbert Herzog via email with any concerns, suggestions or comments.

All rights are reserved to information provided on the website or other information sources. No part of these programs can be reproduced stored in a retrieval system or transcribed in any form or by any means for personal or financial gained without the express written permission of Drs. Niesel and Dr. Herzog.