Medical Discovery NewsBridging the World of Medical Discovery and You

Recent Episodes

Glowing Wounds

MP3 WAV

  • The Battle of Shiloh was a devastating American civil war battle in which both the North and the South suffered heavy losses. But it's also known for the mysterious phenomenon known as Angel's Glow. What glowed were the soldiers' wounds which amazingly gave them a better chance at survival.

    But this mystery wasn't solved until two thousand one by high school students. As the Battle of Shiloh ended, the wounded lay in the muddy field awaiting help. Then some soldiers noticed their wounds glowing greenish-blue in the dark. Though perplexed, physicians saw that soldiers whose wounds glowed had lower infection rates and healed faster. Thus the soldiers coined the term Angel's Glow.

    Fast forward a hundred fifty years, high school student, Bill Martin, got interested after touring the battle site. With his mom's help, who's a microbiologist, Bill and a friend began digging for clues.

    They first identified bacteria that are bioluminescent then examined environmental conditions for any that could have been present in Shiloh in eighteen sixty-two. They focused on the bacterium Photorhabdus luminescens which lives inside soil nematodes, microscopic worms.

    The two have a symbiotic relationship. When the bacteria emits light, it attracts insects, allowing the worm to infect them. Once inside, the worm regurgitates the bacteria into the insects' blood, killing the insect and other toxic microbes present. This may be what happened with Angel's Glow. Soldiers' wounds became contaminated with the nematodes. The worms likely released their toxins and enzymes, essentially cleaning the wound by killing pathogenic bacteria.

    Even though this is not confirmed, it's the best explanation we have thanks to a couple of high school students. You go guys!

More Information

Why Some Wounded Civil War Soldiers Actually Glowed In The Dark ' And Lived Because Of It
"Angel's Glow" was a phenomenon of the Civil War in which soldiers' wounds seemed to glow in the dark. It took 139 years to figure out why...

Photorhabdus luminescens
"Photorhabdus luminescens also known as Xenorhabdus luminescens is a bioluminescent microbe...

Nematodes - the good, the bad and the ugly.
How would you like something worm-like, eight metres long and as thick as a garden hose wriggling (Figure 1) around in your stomach? Well spare a thought for the sperm whale, because that is exactly what it has to put up with! A species of giant nematode (Placentonema gigantissimum) makes its home in the placenta of the sperm whale...

Battle of Shiloh
Also known as the Battle of Pittsburg Landing, the Battle of Shiloh took place from April 6 to April 7, 1862, and was one of the major early engagements of the American Civil War (1861-65)...

Two individuals wearing headphones stand in a recording booth, speaking into microphones with a music stand holding printed pages between them.

 Medicine...

Medicine is constantly advancing – that is a great thing about life in the 21st century. But it doesn’t just happen. Dedicated biomedical scientists are making discoveries that translate into those new medical advances.

Biomedical science is broad, encompassing everything from social science to microbiology, biochemistry, epidemiology, to structural biology and bioinformatics to name just a few areas. And, it can involve basic fundamental biology, the use of AI and chemistry to clinical studies that evaluate new medicines in patients.

No matter the research focus, the goal is always the same, to advance human health. It may take a few months, a few years or for fundamental science, a few decades. Few people make the connection that biomedical science is medicine and that biomedical scientists are working today on the medicine of tomorrow. Our weekly 500-word newspaper columns and 2-minute radio shows and podcasts provide insights into a broad range of biomedical science topics.

Medical Discovery News is dedicated to explaining discoveries in biomedical research and their promise for the future of medicine.

Podcasts

Alternatively, you can copy and paste the following web address (URL) into iTunes as a new subscription:
https://www.medicaldiscoverynews.com/shows/audio/mdnews.rss

You can also search and subscribe to "Medical Discovery News" in the podcast section of iTunes.

The www.medicaldiscoverynews.com web site and Medical Discovery News radio program (Program) are made possible by The University of Texas Medical Branch at Galveston (UTMB)as a community service and are intended to advance UTMB's mission of providing scholarly teaching, innovative scientific investigation, and state-of-the-art patient care in a learning environment to better the health of society and its commitment to the discovery of new innovative biomedical and health services knowledge leading to increasingly effective and accessible health care for the citizens of Texas.

All information provided on the web site and in the Program is for informational purposes only and is not intended for use as diagnosis or treatment of a health problem or as a substitute for consulting a licensed medical professional. Any information obtained by participating as a web site visitor or program listener is not intended to and should not be considered to constitute medical advice.

Thoughts and opinions expressed on the Program or on the website are those of the authors or guests and do not necessarily reflect the opinions of UTMB. The provision of links to other websites is not to be construed as written or implied sponsorship or endorsement of such websites by UTMB.

Please contact Dr. David Niesel or Dr. Norbert Herzog via email with any concerns, suggestions or comments.

All rights are reserved to information provided on the website or other information sources. No part of these programs can be reproduced stored in a retrieval system or transcribed in any form or by any means for personal or financial gained without the express written permission of Drs. Niesel and Dr. Herzog.