Medical Discovery NewsBridging the World of Medical Discovery and You

Recent Episodes

Public Health Concerns for Neanderthals

MP3 WAV

  • We're all living out the nightmare of the COVID zoonosis which is when a disease jumps from animals to humans. But the phenomenon is ancient as evidenced by the "Old Man of La Chapelle". He's a fossilized Neanderthal skeleton discovered in a French cave in nineteen-o-eight. Neanderthals disappeared forty thousand years ago.

    New analysis suggests that an infection he got from butchering animals led to changes in his bones that had long been mistaken for osteoarthritis. Even two years ago, an analysis reported that his bones showed signs of advanced osteoarthritis in the spine and hip. The new report came after scientists compared the impact of bone changes from various diseases. It led them to conclude inflammation was a major factor and to a diagnosis of Brucella infection.

    People today get it from infected animals, contaminated foods, and aerosols. Brucellosis remains the leading zoonotic bacterial infection worldwide, mostly from cattle, sheep, goats, even dogs. It's rare in the US since animals are vaccinated and dairy is pasteurized. Symptoms include fever, fatigue, pain in muscles and joints. In some people the symptoms never go away and include arthritis, swelling of the testicles and heart, and neurologic symptoms. For years, the Neanderthal's remains made us think they stooped when they didn't.

    Knowing that zoonosis has plagued not only us but our prehistoric cousins is sobering and warns us public health vigilance is key to our well-being.

More Information

Ancient case of disease spillover discovered in Neanderthal man who got sick butchering raw meat
Scientists studying ancient disease have uncovered one of the earliest examples of spillover -- when a disease jumps from an animal to a human -- and it happened to a Neanderthal man who likely got sick butchering or cooking raw meat...

Possible vertebral brucellosis infection in a Neanderthal
The La Chapelle-aux-Saints 1 skeleton of an old (>60-year-old) male Neanderthal is renowned for the advanced osteoarthritis of its spinal column and hip joint, and their implications for posture and lifestyle in these Mid- to Late Pleistocene humans. Reassessment of the pathologic lesions reveals erosions at multiple non-contiguous vertebrae and reactive bone formation extending far beyond the left hip joint, which suggests the additional diagnosis of brucellosis. This implies the earliest secure evidence of this zoonotic disease in hominin evolution...

homo neanderthalensis: la chapelle-aux-saints
The fossil La Chappelle-aux-Saints is represented by a nearly complete edentulous cranium and mandible...

Two individuals wearing headphones stand in a recording booth, speaking into microphones with a music stand holding printed pages between them.

 Medicine...

Medicine is constantly advancing – that is a great thing about life in the 21st century. But it doesn’t just happen. Dedicated biomedical scientists are making discoveries that translate into those new medical advances.

Biomedical science is broad, encompassing everything from social science to microbiology, biochemistry, epidemiology, to structural biology and bioinformatics to name just a few areas. And, it can involve basic fundamental biology, the use of AI and chemistry to clinical studies that evaluate new medicines in patients.

No matter the research focus, the goal is always the same, to advance human health. It may take a few months, a few years or for fundamental science, a few decades. Few people make the connection that biomedical science is medicine and that biomedical scientists are working today on the medicine of tomorrow. Our weekly 500-word newspaper columns and 2-minute radio shows and podcasts provide insights into a broad range of biomedical science topics.

Medical Discovery News is dedicated to explaining discoveries in biomedical research and their promise for the future of medicine.

Podcasts

Alternatively, you can copy and paste the following web address (URL) into iTunes as a new subscription:
https://www.medicaldiscoverynews.com/shows/audio/mdnews.rss

You can also search and subscribe to "Medical Discovery News" in the podcast section of iTunes.

The www.medicaldiscoverynews.com web site and Medical Discovery News radio program (Program) are made possible by The University of Texas Medical Branch at Galveston (UTMB)as a community service and are intended to advance UTMB's mission of providing scholarly teaching, innovative scientific investigation, and state-of-the-art patient care in a learning environment to better the health of society and its commitment to the discovery of new innovative biomedical and health services knowledge leading to increasingly effective and accessible health care for the citizens of Texas.

All information provided on the web site and in the Program is for informational purposes only and is not intended for use as diagnosis or treatment of a health problem or as a substitute for consulting a licensed medical professional. Any information obtained by participating as a web site visitor or program listener is not intended to and should not be considered to constitute medical advice.

Thoughts and opinions expressed on the Program or on the website are those of the authors or guests and do not necessarily reflect the opinions of UTMB. The provision of links to other websites is not to be construed as written or implied sponsorship or endorsement of such websites by UTMB.

Please contact Dr. David Niesel or Dr. Norbert Herzog via email with any concerns, suggestions or comments.

All rights are reserved to information provided on the website or other information sources. No part of these programs can be reproduced stored in a retrieval system or transcribed in any form or by any means for personal or financial gained without the express written permission of Drs. Niesel and Dr. Herzog.