Medical Discovery NewsBridging the World of Medical Discovery and You

Recent Episodes

Spit Makes It Worse

MP3 WAV

  • The Zika virus isn't only spread by mosquitos, the infection is actually made worse by mosquito spit! The female mosquito needs blood in order to produce her eggs. So when she feeds she's inserting a flexible straw that can seek out a blood vessel. From the moment she probes the skin, the mosquito starts salivating. That's also where pathogens make full use of both hosts. In the mosquito's saliva are molecules that numb the skin and block our normal immune response.

    To test whether mosquito saliva makes the Zika infection worse, researchers in a study used a less harmful relative of Zika called Simliki Forest Virus or SFV. When the virus enters the body, it triggers an immune response that includes macrophages which normally help orchestrate the body's defenses against an infection. Instead, researchers saw that the macrophages were infected by the virus and helped spread the virus throughout the body.

    However, when they did the study without mosquito spit, the viral infection could not spread as much, produce as much virus in the body, and was not as lethal. The same can be said of Zika where the virus has evolved to take advantage of and control elements in both its mosquito and human hosts.

    What exacerbates the problem is humans develop high enough levels of the virus to infect other uninfected mosquitos, spreading the disease faster .This surely will not be the last mosquito-borne virus to arise from nature, so use bug repellant or other strategies to avoid being bitten by a mosquito. If you are considering pregnancy, be sure to follow the CDC guidelines and talk to your physician about the precautions you should take.

More Information

Mosquito spit helps viruses make us sick
When a mosquito infects you with a viral disease such as Zika or dengue, it does more than just deliver a few virus particles under your skin...

The history of Zika virus
The rise in the spread of Zika virus has been accompanied by a rise in cases of microcephaly and Guillain-Barr' syndrome...

What REALLY happens when a mosquito bites
Scientists capture how the parasite sucks blood in a gruesome video...

Two individuals wearing headphones stand in a recording booth, speaking into microphones with a music stand holding printed pages between them.

 Medicine...

Medicine is constantly advancing – that is a great thing about life in the 21st century. But it doesn’t just happen. Dedicated biomedical scientists are making discoveries that translate into those new medical advances.

Biomedical science is broad, encompassing everything from social science to microbiology, biochemistry, epidemiology, to structural biology and bioinformatics to name just a few areas. And, it can involve basic fundamental biology, the use of AI and chemistry to clinical studies that evaluate new medicines in patients.

No matter the research focus, the goal is always the same, to advance human health. It may take a few months, a few years or for fundamental science, a few decades. Few people make the connection that biomedical science is medicine and that biomedical scientists are working today on the medicine of tomorrow. Our weekly 500-word newspaper columns and 2-minute radio shows and podcasts provide insights into a broad range of biomedical science topics.

Medical Discovery News is dedicated to explaining discoveries in biomedical research and their promise for the future of medicine.

Podcasts

Alternatively, you can copy and paste the following web address (URL) into iTunes as a new subscription:
https://www.medicaldiscoverynews.com/shows/audio/mdnews.rss

You can also search and subscribe to "Medical Discovery News" in the podcast section of iTunes.

The www.medicaldiscoverynews.com web site and Medical Discovery News radio program (Program) are made possible by The University of Texas Medical Branch at Galveston (UTMB)as a community service and are intended to advance UTMB's mission of providing scholarly teaching, innovative scientific investigation, and state-of-the-art patient care in a learning environment to better the health of society and its commitment to the discovery of new innovative biomedical and health services knowledge leading to increasingly effective and accessible health care for the citizens of Texas.

All information provided on the web site and in the Program is for informational purposes only and is not intended for use as diagnosis or treatment of a health problem or as a substitute for consulting a licensed medical professional. Any information obtained by participating as a web site visitor or program listener is not intended to and should not be considered to constitute medical advice.

Thoughts and opinions expressed on the Program or on the website are those of the authors or guests and do not necessarily reflect the opinions of UTMB. The provision of links to other websites is not to be construed as written or implied sponsorship or endorsement of such websites by UTMB.

Please contact Dr. David Niesel or Dr. Norbert Herzog via email with any concerns, suggestions or comments.

All rights are reserved to information provided on the website or other information sources. No part of these programs can be reproduced stored in a retrieval system or transcribed in any form or by any means for personal or financial gained without the express written permission of Drs. Niesel and Dr. Herzog.