Medical Discovery NewsBridging the World of Medical Discovery and You

Recent Episodes

portrait of Napoleon on a horse

The Bacteria That Helped To Defeat Napoleon

MP3 WAV

  • Different generations of leaders and soldiers learned the same lesson the hard way.  Both Napoleon and Hitler invaded Russia and both armies failed.  We now know from a study that two additional diseases plagued Napoleon’s troops along with hunger, cold, and harassment from Russian troops. 

    In June of 1812, Napolean’s army of more than 600,000, Europe’s largest, crossed into Russia. Facing a much smaller Russian army, he believed he’d win in a month. But the Russians used the Fabian strategy, a scorched earth approach that involved retreating and avoiding large scale battles while destroying resources as they went. 

    So even while Napoleon captured Moscow, it was abandoned and set ablaze with few supplies and winter coming on. By the time he retreated in October and crossed into France in December, just one-sixth of his army remained. Researchers studying DNA from the remains of those soldiers learned they had suffered from typhus and trench fever, but the methods they used could only identify microbes they specifically looked for.  

    New recent work used more advanced techniques that could analyze millions of DNA fragments on soldiers’ teeth for a wide array of pathogens simultaneously.  This turned up two new bacteria responsible for decimating Napoleon’s army: one that causes paratyphoid fever and another that causes relapsing fever. Now we have a clearer picture of what happened in one of history’s major chapters.  

More Information

DNA from Napoleon's 1812 army identifies pathogens likely responsible for the army's demise during retreat from Russia
In the summer of 1812, French emperor Napoleon Bonaparte led about half a million soldiers to invade the Russian Empire. But by December, only a fraction of the army remained alive. Historical records suggest that starvation, cold, and typhus led to their demise.

How Napoleon’s army met its doom: DNA reveals surprise illnesses had a role
Remains of some of the 300,000 soldiers who died on the retreat from Moscow reveal two bacterial diseases that probably added to the death count.

Paratyphoid fever and relapsing fever in 1812 Napoleon's devastated army
During Napoleon’s retreat from Russia in 1812, countless soldiers of the French army succumbed to infectious diseases, but the responsible pathogen or pathogens remain debated. We recovered and sequenced ancient DNA from the teeth of 13 soldiers who, based on historical records, likely died from infectious diseases, aiming to identify the pathogens responsible for their deaths.

Two individuals wearing headphones stand in a recording booth, speaking into microphones with a music stand holding printed pages between them.

 Medicine...

Medicine is constantly advancing – that is a great thing about life in the 21st century. But it doesn’t just happen. Dedicated biomedical scientists are making discoveries that translate into those new medical advances.

Biomedical science is broad, encompassing everything from social science to microbiology, biochemistry, epidemiology, to structural biology and bioinformatics to name just a few areas. And, it can involve basic fundamental biology, the use of AI and chemistry to clinical studies that evaluate new medicines in patients.

No matter the research focus, the goal is always the same, to advance human health. It may take a few months, a few years or for fundamental science, a few decades. Few people make the connection that biomedical science is medicine and that biomedical scientists are working today on the medicine of tomorrow. Our weekly 500-word newspaper columns and 2-minute radio shows and podcasts provide insights into a broad range of biomedical science topics.

Medical Discovery News is dedicated to explaining discoveries in biomedical research and their promise for the future of medicine.

Podcasts

Alternatively, you can copy and paste the following web address (URL) into iTunes as a new subscription:
https://www.medicaldiscoverynews.com/shows/audio/mdnews.rss

You can also search and subscribe to "Medical Discovery News" in the podcast section of iTunes.

The www.medicaldiscoverynews.com web site and Medical Discovery News radio program (Program) are made possible by The University of Texas Medical Branch at Galveston (UTMB)as a community service and are intended to advance UTMB's mission of providing scholarly teaching, innovative scientific investigation, and state-of-the-art patient care in a learning environment to better the health of society and its commitment to the discovery of new innovative biomedical and health services knowledge leading to increasingly effective and accessible health care for the citizens of Texas.

All information provided on the web site and in the Program is for informational purposes only and is not intended for use as diagnosis or treatment of a health problem or as a substitute for consulting a licensed medical professional. Any information obtained by participating as a web site visitor or program listener is not intended to and should not be considered to constitute medical advice.

Thoughts and opinions expressed on the Program or on the website are those of the authors or guests and do not necessarily reflect the opinions of UTMB. The provision of links to other websites is not to be construed as written or implied sponsorship or endorsement of such websites by UTMB.

Please contact Dr. David Niesel or Dr. Norbert Herzog via email with any concerns, suggestions or comments.

All rights are reserved to information provided on the website or other information sources. No part of these programs can be reproduced stored in a retrieval system or transcribed in any form or by any means for personal or financial gained without the express written permission of Drs. Niesel and Dr. Herzog.