Medical Discovery NewsBridging the World of Medical Discovery and You

Recent Episodes

cannabis leaf

Your Genes and Cannabis

MP3 WAV

  • So far, 37 states have legalized marijuana for medical purposes, while 19 states and the  District of Columbia have also legalized its recreational use.  But recent reports show up to one-third of cannabis users get Canabis Use Disorder or CanUD, that’s cannabis addiction or using cannabis in a way that damages their health.   

    Now a new study that looked at 1 million genomes has found regions of our DNA that appear linked to cannabis addiction and even schizophrenia and lung cancer. Researchers used large medical datasets that include US veterans, mostly people of European descent but also some African, East Asian, and mixed ancestries.  

    The genes involved in the disorder were in regions close to the brain’s reward system involved in addiction. The same areas are linked to cigarette smoking, substance abuse, post-traumatic stress disorder, and lung cancer. The study also affirmed a stronger link between CanUD and schizophrenia. The data suggests that cannabis use “is the most preventable risk factor” for the development of schizophrenia.  Yet a National Survey on Drug Use and Health revealed that cannabis use jumped to seventeen percent from eleven percent in twenty-twenty-two and growing.  

    It serves as a warning that just like food, drugs and chemicals we ingest or are exposed to affect our health. People must understand the consequences before deciding to imbibe. 

    We are Drs. David Niesel and Norbert Herzog, at UTMB and Quinnipiac University, where biomedical discoveries shape the future of medicine.   For much more and our disclaimer go to medicaldiscoverynews.com or subscribe to our podcast. Sign up for expanded print episodes at www.illuminascicom.com or our podcasts at:  Medical Discovery News (buzzsprout.com) 

More Information

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications
As recreational use of cannabis is being decriminalized in many places and medical use widely sanctioned, there are growing concerns about increases in cannabis use disorder (CanUD), which is associated with numerous medical comorbidities. A genetically informed causal relationship analysis indicated a possible effect of genetic liability for CanUD on lung cancer risk, suggesting potential unanticipated future medical and psychiatric public health consequences that require further study to disentangle from other known risk factors such as cigarette smoking.

Massive genetic study finds genes linked to cannabis addiction
Data from more than one million genomes offer fresh insights into excessive cannabis use and its relationship to other diseases.

Genetic risks behind 'cannabis use disorder' found in huge study
In a study that included genetic data from more than 1 million people, scientists started to unravel the genetics of cannabis use disorder.

Two individuals wearing headphones stand in a recording booth, speaking into microphones with a music stand holding printed pages between them.

 Medicine...

Medicine is constantly advancing – that is a great thing about life in the 21st century. But it doesn’t just happen. Dedicated biomedical scientists are making discoveries that translate into those new medical advances.

Biomedical science is broad, encompassing everything from social science to microbiology, biochemistry, epidemiology, to structural biology and bioinformatics to name just a few areas. And, it can involve basic fundamental biology, the use of AI and chemistry to clinical studies that evaluate new medicines in patients.

No matter the research focus, the goal is always the same, to advance human health. It may take a few months, a few years or for fundamental science, a few decades. Few people make the connection that biomedical science is medicine and that biomedical scientists are working today on the medicine of tomorrow. Our weekly 500-word newspaper columns and 2-minute radio shows and podcasts provide insights into a broad range of biomedical science topics.

Medical Discovery News is dedicated to explaining discoveries in biomedical research and their promise for the future of medicine.

Podcasts

Alternatively, you can copy and paste the following web address (URL) into iTunes as a new subscription:
https://www.medicaldiscoverynews.com/shows/audio/mdnews.rss

You can also search and subscribe to "Medical Discovery News" in the podcast section of iTunes.

The www.medicaldiscoverynews.com web site and Medical Discovery News radio program (Program) are made possible by The University of Texas Medical Branch at Galveston (UTMB)as a community service and are intended to advance UTMB's mission of providing scholarly teaching, innovative scientific investigation, and state-of-the-art patient care in a learning environment to better the health of society and its commitment to the discovery of new innovative biomedical and health services knowledge leading to increasingly effective and accessible health care for the citizens of Texas.

All information provided on the web site and in the Program is for informational purposes only and is not intended for use as diagnosis or treatment of a health problem or as a substitute for consulting a licensed medical professional. Any information obtained by participating as a web site visitor or program listener is not intended to and should not be considered to constitute medical advice.

Thoughts and opinions expressed on the Program or on the website are those of the authors or guests and do not necessarily reflect the opinions of UTMB. The provision of links to other websites is not to be construed as written or implied sponsorship or endorsement of such websites by UTMB.

Please contact Dr. David Niesel or Dr. Norbert Herzog via email with any concerns, suggestions or comments.

All rights are reserved to information provided on the website or other information sources. No part of these programs can be reproduced stored in a retrieval system or transcribed in any form or by any means for personal or financial gained without the express written permission of Drs. Niesel and Dr. Herzog.