
07.22.2025 Seminar Series: Federated Evaluation of Data to Enhance Pain Research among Adults in Later Life (FEDERAL)
Seminar Series
Tuesday, July 22, 2025
12:00-1:00PM
Join Zoom Webinar: https://www.zoomgov.com/j/1604768501?pwd=frf3YFpm12PHBN90uzSJDsa5K33q7u.1
Deep Learning Approach to Nonparametric Propensity Score Estimation with Optimized Covariate Balance
Presented by: Corey Simon, PhD and Rebecca North, PhD, Duke University
Abstract: Older adults have the highest prevalence of chronic pain and yet geriatric pain management remains suboptimal. Data pooling is necessary to inform evidence-based guidelines that improve geriatric pain management. The traditional data pooling approach employs data use agreements (DUA) to transfer data from multiple institutions to a single site. However, DUA are time intensive; and prohibited by health system ownership, private health information, and indemnification clauses. And innovative alternative is federated evaluation: identifiable data remains housed at institutions, statistical code is shared (via a common data model [CDM]), and source data transformed and aggregated. To this end, the FEDERAL study is leveraging existing CDMs, local source data, and Duke Pepper Center resources to develop a CDM with code specifically for geriatric pain research. The CDM and code will be piloted at Yale and Mount Sinai Pepper Centers to evaluate the feasibility and utility of conducting pain and opioid medication research in a pooled population of older adults. Goals for FEDERAL include the initiation of evidence-based guidelines for geriatric pain management, expedited data pooling for 11 legacy studies in the Pain Management Collaboratory, and preliminary data generation for an R01 proposal to expand the FEDERAL CDM network.
Virtual Seminar: Contact Anirudh Babu (asbabu@utmb.edu) for additional information.
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Anirudh Babu, Statistical Assistant
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Email: asbabu@utmb.edu
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