Education:
B.S.-Biology, 1986, University of Texas El Paso, El Paso, TX
M.S.-Biology, 1990, University of Texas El Paso, El Paso, TX
Ph.D.-Biomedical Sciences (Environmental Toxicology), 1997, University of Texas Medical Branch, Galveston, TX
Post-Doctoral Fellow, 1997, Texas A & M University, College Station, TX
Senior Post-Doctoral Fellow, 2000, University of Texas Medical Branch, Galveston, TX

Research Interests:

• Community Education and engagement
• Assessment of Indoor Air Quality
• Effects of Ambient Environmental Air Toxicants
• Role of Particulates on Lung Inflammation
• Tobacco and E-cigarette Exposure on Lung Physiology

Selected Publications:

1. Hallberg L. M., Ward J. B., Wickliffe J.K., Ameredes B.T., Advanced Collaborative Emissions Study Auxiliary Findings on 2007-Compliant Diesel Engines: A Comparison with Diesel Exhaust Genotoxicity Effects Prior to 2007. Environmental Health Insights 2017,11, 1-13, doi: 10.1177/1178630217714215
2. Hartman JH, Miller GP, Caro AA, Byrum SD, Orr LM, Mackintosh SG, Tackett AJ, Macmillion-Crow LA, Hallberg LM, Ameredes BT, Boysen G. 1,3-butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in collaborative cross mice. Toxicology 2017 Mar 1;378: 114-124. doi: 10.1016/j.tox.2017.01.005. Epub 2017 Jan 9.
3. Hallberg L.M, Ward JB, Hernandez C, Ameredes BT, Wickliffe JK. (2015) Part 3. Assessment of genotoxicity and oxidative damage in rats after chronic exposure to new-technology diesel exhaust in ACES bioassay In: Advanced Collaborative Emissions Study (ACES): Lifetime Cancer and Non-Cancer Assessment in Rats Exposed to New-Technology Diesel Exhaust. Research. Boston, MA: Health Effects Institute; 184, 83-106.  ACES Publications
4. Srikanth Kotapati; Dewakar Sangaraju; Amanda Esades; Lance Hallberg; Vernon E Walker; James A Swenberg; Natalia Y Tretyakova, Bis-butanediol-mercapturic acid (bis-BDMA) as a urinary biomarker of metabolic activation of butadiene to its ultimate carcinogenic species. Carcinogenesis. 2014; 35(6):1371-1378. doi: 10.1093/carcin/bgu047
5. Barreno, R. X., J. B. Richards, D. J. Schneider, K. R. Cromar, A. J. Nadas, C. B. Hernandez, L. M. Hallberg, R. E. Price, S. S. Hashmi, M. R. Blackburn, I. U. Haque, and R. A. Johnston, (2013) Endogenous Osteopotin Promotes Ozone-Induced Neutrophil Recruitment to the Lungs and Airway Hyperresponsiveness to Methacholine, Am J Physiol Lung Cell Mol Physiol (accepted May 10, doi:10.1152/ajplung.00080.2013)
6. Hallberg, L.M., J.B. Ward, C. Hernandez, B.T. Ameredes, J.K. Wickliffe, (2012) Part 3. Assessment of Genotoxicity and Oxidative Stress after exposure to Diesel Exhaust emission from U.S. 2007-compliant Diesel Engines: Report on 1- and 3-Month Exposures in the ACES Bioassay, Research Report Health Effects Institute 166, 163-184.
7. Heung M. Lee, Lance M. Hallberg, George H. Greeley, Jr. and Ella W. Englander, (2010) Inhalation of Combustion Smoke Inhibits Rat Brain Mitochondria Respiratory Complexes to a Greater Extent than Inhalation of Carbon Monoxide, Inhalation Toxicology Aug. 22(9), 770-777. doi: 10.3109/08958371003770315
8. Wickliffe, J. K., S. M. Herring, L. M. Hallberg, L. A. Galbert, O. E. Masters III, M. M. Ammenheuser, J. Xie, E. C. Friedberg, R. S. Lloyd, S. Z. Abdel-Rahman, J. B. Ward Jr., (2007) Detoxification of olefinic epoxides and nucleotide excision repair of epoxide-mediated DNA damage: insights from animal models examining human sensitivity to 1,3-butadiene, Chemico-Biological Interactions, 166, 226-231.
9. Hallberg, L.M., Y. Ikeno, E. Englander, and G.H. Greeley Jr. (2000) Effects of aging and caloric restriction on IGF-I, IGF-I receptor, IGFBO-3 and IGFBP-4 gene expression in the rat stomach and colon, Regul. Pept. May 10, 89(1-3), 37-44. DOI: 10.1016/S0167-0115(00)00095-1
10. Hallberg, L.M., Bechtold, W.E., Grady, J., Legator, M.S., and Au, W.W. (1997) Abnormal DNA repair activities in lymphocytes of workers exposed to 1,3-butadiene. Mutat. Res., 383, 213-221. DOI: 10.1016/s0921-8777(97)00004-9