Wayne R. Snodgrass
Wayne R. Snodgrass, M.D., Ph.D. Assistant Professor, Department Pharmacology and Toxicology

Contact Information:
Phone: (409) 772-9612
Fax: (409) 772-9642
Email: wsnodgra@utmb.edu

Education: 
B.S. - 1968 - Butler University, Indianapolis, IN
M.S. - 1971 - Indiana University, Indianapolis, IN
M.D. - 1972 - Indiana University, Indiana, IN
Ph.D. - 1976 - Indiana University, Indiana, IN

Research Interests: 

  • Use of cytochrome P-450 isoenzyme patterns to predict individual toxicity risk for drugs and chemicals that undergo metabolic activation. 
  • Sedation and analgesia. 
  • Use of anti-oxidant/NMDA antagonist therapies to decrease anoxic brain injury. 
  • Use of urinary thioether excretion as an index of exposure to environmental chemicals. 
  • Use of gastrointestinal dialysis to enhance removal of environmental/occupational chemicals from deep compartment body storage sites. 
  • Application of stochastic control theory Bayesian population pharmacokinetics to improve individual patient therapeutics.

Selected Publications: 

  1. Snodgrass WR: Valproic acid medical toxicology. IN: Brent J et al: Critical Care Toxicology. Diagnosis and Management of the Critically Poisoned Patient. Elsevier Mosby, Philadelphia PA, 2005:565—570 
  2. Klein, G. and Snodgrass, W.R. (2000) Food toxins and poisons from microorganisms. The Cambridge World History of Food, vol II, Kiple K.F. and Ornelas, K.C. (eds) Cambridge University Press, NY, 1694-1703. 
  3. Snodgrass, W.R. (1996) Clinical Toxicology. Casarett and Doull's Toxicology: The Basic Science of Poisons, 5th ed, Klaassen CD, ed, McGraw-Hill, NY. 969-986. 
  4. Snodgrass WR: Use of herbal products in children: risks and unproven benefits. IN: Neonatal and Pediatric Pharmacology. Therapeutic Principles in Practice. Lippincott Williams & Wilkins, Philadelphia PA, 2005:841—847 
  5. Albers, J.W., Cole P., Greenberg, R.S., Mendel J.S., Monson, R.R., Ross, J.H., Snodgrass, W.R., Spurgeon, A., and van Gemert, M. (1999) Analysis of chlorpyrifos exposure and human health: expert panel report. J. Toxicol Environ Health. 2:301-324.