The Pepper Center at UTMB:
Continuously Funded Since 2000

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The UTMB Claude D. Pepper Older Americans Independence Center (OAIC) is the home of a diverse multidisciplinary team of investigators with complementary research interests. The Center supports investigators, research, and expertise in gerontology to accomplish the OAIC mission: To Improve Physical Function and Independence in Older Adults.

Current Events

Productivity Metrics

  • Publications (2000-2022): over 740
  • Scholars Trained (2000-2022): 33
  • External projects currently supported: 33

Contact Us

University of Texas Medical Branch
Sealy Center on Aging (SCoA)
301 University Blvd.
Galveston, TX 77555-0177
Directions and Maps
Phone: (409) 747-0008

Featured News

Mechanomedicine of Aging Symposium to be held on campus and webcast July 1st

Jun 28, 2022, 08:53 AM by SCOA


Mechanomedicine of Aging Symposium
1-5 PM on July 1, 2022 in HEC 3.222
Organized by Mechanomedicine Center
All UTMB Researchers Invited

 Join Webcast During the Event

With the increase in lifespan from better medical treatments, there is great interest in mitigating the quality-of-life compromises that come with aging. Much evidence indicates that exercise inhibits many aging processes and does so through the mechanical reversal of senescence at a cellular level. We will explore some of the molecular mechanisms whereby exercise and other mechanical effects can an inhibitor reverse the senescence process.

We want to stimulate interactions at UTMB on the studies of aging with particular emphasis on the molecular mechanisms that can mitigate aging through exercise or other mechanical activities. Complex metabolic and signaling pathways are altered with cell senescence and the increase in the percentage of senescent cells with age underlies many aging abnormalities. These include diabetes, arthritis, susceptibility to infection, cardiovascular and other disorders.


  • 1:00-1:10 Introduction
  • 1:10-1:50 Investigating Mechanisms and Treatment of Skeletal Musde Atrophy - presented by Plenary Prof. Chris Adams
  • 1:50-2:20 Impaired Muscle Anabolism in Aging - presented by Prof. Blake Rasmussen
  • 2:20-2:40 Consequences of Altered Chromatin Structure during MSC Aging: Increased Cryptic Transcription and Disrupted Super Enhancer-Promoter Looping - presented by Dr. Brenna McCauley
  • 2:40-3:00 Increased Stem Cell Expansion by Ultrasound Rejuvenation of Senescence - presented by Dr. Sanjay Kureel
  • 3:00-3:20 Break
  • 3:20-3:50 Aging Regulation by Chromatin-Regulated Stress Response Mechanisms - presented by Assoc. Prof Weiwei Dang
  • 3:50-4:20 The Significance of Sarcopenia - presented by Prof. Elena Volpi
  • 4:20-4-40 Delineating the Role of Resilience in Non-human Primate Aging using Baboon Cell Models - presented by Dr. Daniel A. Adekunbi
  • 4:40-5:10 Ultrasound Rejuvenation of Senescent Cells In Vitro and In Vivo - presented by Prof. Michael Sheetz
  • 5:10-7:00 Reception



301 University Blvd. Galveston, TX 77555-0177 | p 409.747.0008 | f 409.772.8931
The Claude D. Pepper Older Americans Independence Center Award #P30-AG024832 is funded by
the National Institute on Aging (NIA), part of the United States Department of Health and Human Services.