If you are interested in learning about clinical trials, we can advise you about what studies are ongoing and explain the clinical trial process in detail to guide you toward making an informed decision. Contact the Clinical Trials Group at scvd.ctg@utmb.edu.

Current Studies

H7N9 Bird Flu Vaccine Study for 19-64 Year Olds

PURPOSE: Vaccination is currently the most effective way of controlling flu and preventing its illness and complications. In March, 2013 a new avian (bird) flu virus, causing severe disease or death in infected patients, was reported in China. The purpose of this study is to test the safety and effectiveness of a new bird flu vaccine (H7N9 flu shot) as part of the United States government preparedness in case this virus spreads world-wide.We are recruiting healthy male or non-pregnant female volunteers, ages 19 to 64 years old, who are able to attend 5 clinic visits and reply to 6 phone calls needed for new avian (bird) flu vaccine study. – Enrolling Now

Dengue Vaccine Study for 18-45 Year Olds

PURPOSE: Dengue fever is caused by infection with the dengue virus. The virus is transmitted from human to human by mosquitoes. Infection with a dengue virus can result in a range of symptoms, from subclinical disease to debilitating but transient dengue fever to life-threatening dengue hemorrhagic fever (DHF) to dengue shock syndrome (DSS). An estimated 36 million cases of dengue fever occur annually, which results in around 2.3 million cases of DHF and an estimated 20,000 deaths, primarily in children. Dengue is considered the most serious vector-borne disease in children, especially in countries in Southeast Asia, where more than 50% of all dengue cases and dengue related deaths occur in children below the age of 15 years. However, adults are also frequently at risk and, in some areas, have a greater incidence of disease than children. Mosquito control efforts in endemic areas have been ineffective in preventing dengue outbreaks or in preventing further geographical spread of the disease. Since World War II, the four dengue viruses have spread worldwide and are endemic in Asia, Central and South America including Colombia, the Caribbean, the Pacific Islands, and parts of Africa and Australia. Clearly, there is a need for a safe and effective vaccine that will protect against dengue infection. – Enrolling Now

Measles, Mumps, Rubella, Varicella Vaccine Study for 12-23 Month Olds

PURPOSE:  A Phase III Double-Blind, Randomized, Multicenter, Controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of Measles, Mumps, Rubella, Varicella (MMRV) Vaccine Made with an Alternative Manufacturing Process (AMP). – Enrolling Now

Herpes Zoster (Shingles) Vaccine Study

PURPOSE: The purpose of this study is to learn about the safety and effectiveness of an inactivated (not live) experimental herpes zoster vaccine in people with certain cancers. Zoster (HZ), or shingles, is a reactivation of the virus varicella which initially causes chickenpox. Following a chicken pox infection, the virus remains dormant in the nervous system until it reactivates, producing HZ. HZ is usually characterized by a painful, blistery skin rash. People with a lowered immune system have a higher chance of HZ, compared to the general population, and are at increased risk for developing severe and life-threatening complications. The only vaccine right now for shingles is a live vaccine and people who have lowered immune system should not take this vaccine. – Enrolling Now



Last updated September 2013