Description: Vaccinology: An Essential Guide is a perfect tool designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. In a clear
practical format, this book outlines the entire vaccine development process from conceptualization and basic immunological principles through clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice
of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, economic and geographical issues that drive vaccine development and trials, it also
presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterrorism.
There are also sections devoted to veterinary vaccines and associated regulatory processes.The book is also suitable for everyone involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference
book Vaccinology: Principles and Practice.
About the Editors
Drs. Alan Barrett and Gregg Milligan are world-renowned experts in vaccine development and viral immunology. Dr. Barrett, a recognized leader in the biology of flaviviruses, researches tropical virus diseases such as dengue, West Nile, yellow
fever and Japanese encephalitis. He has made important contributions to molecular aspects of immunogens and preclinical development of candidate vaccines for these diseases, and studies on the current yellow fever 17D vaccine. Dr. Milligan's
research focuses on the innate and adaptive immune responses to herpes viruses. Additionally, he examines the linkage of the innate immune response to vaccines with the development of adaptive immune responses and the role of tissue-resident
immune memory cells in protection against virus infections and disease.