Current Studies

Last updated March 23, 2021

Studies currently being conducted by the SIVS Clinical Trials Program.
For more information click on links to go to ClinicalTrials.gov, or contact (409) 772 5278, Email: sivsctp@utmb.edu.

Recruiting

Current Studies - Recruiting

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NCT04708041: Safety and Immunogenicity of Extended 2-dose Regimens of 9-valent Human Papillomavirus (9vHPV) Vaccine (V503-069)

Recruiting Now!

Sponsor: Merck Sharp & Dohme Corp.
Principal Investigator: Richard Rupp, MD

For more information click here
NCT04642079: Safety and Immunogenicity Study of 20vPnC in Healthy Children 15 Months Through 17 Years of Age

Recruiting Now!

For more information, please visit www.nexxstep14study.com
or contact Robert Cox, RN 409-772-5278 sivsctp@utmb.edu

Sponsor: Pfizer Inc.
Principal Investigator: Richard Rupp, MD

For clinicaltrials.gov information, click here
NCT04525599: A Study to Assess the Safety, Tolerability and Immunogenicity of ASP3772, a Pneumococcal Vaccine, in Toddlers 12 to 15 Months of Age in Comparison to an Active Comparator

Recruiting Now!

For more information, please visit www.VaccineStudyForKids.com
or contact Robert Cox, RN 409-772-5278 or sivsctp@utmb.edu

Sponsor: Astellas Pharma Global Development Inc. (APGD)
Principal Investigator: Richard Rupp, MD

For clinicaltrials.gov information, click here
NCT04144348: Safety and Immunogenicity of mRNA-1653, a Combined Human Metapneumovirus (hMPV) and Parainfluenza Virus Type 3 (PIV3) Vaccine, in Healthy Adults, and Children 12-36 Months of Age With Serologic Evidence of Prior Exposure

Recruiting Soon!
Sponsor: ModernaTX, Inc.
Principal Investigator: Richard Rupp, MD

For more information click here
A Phase 3 Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Lyophilized Formulation of BNT162b2 Against COVID-19 in Healthy Adults

Recruiting Now!
Sponsor: Pfizer Inc.
Principal Investigator: Richard Rupp, MD

For more information click here

Active, Not Recruiting

Current Studies - Active, Not Recruiting

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NCT04470427: A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19

Sponsor: ModernaTX, Inc.
Principal Investigator: Richard Rupp, MD

For more information click here
NCT04368728: Study to Describe the Safety, Tolerability, Immunogenicity, and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals

Sponsor: Pfizer Inc.
Principal Investigator: Richard Rupp, MD

For more information click here
NCT04199689: Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)

Sponsor: Merck Sharp & Dohme Corp.
Principal Investigator: Richard Rupp, MD

For more information click here
NCT03893448: Safety, Tolerability, and Immunogenicity of V114 in Healthy Infants (V114-029) (PNEU-PED)

Sponsor: Merck Sharp & Dohme Corp.
Principal Investigator (Galveston): Richard Rupp, MD
Principal Investigator (Bay Colony): Marcela Navarro, MD

For more information click here
NCT03738241: A Phase II Study to Assess the Safety, Reactogenicity and Immunogenicity of a Single Dose of 2017 A/H7N9 Inactivated Influenza Vaccine (IIV) Administered IM With or Without AS03 Adjuvant in 2013 A/H7N9 IIV Primed or A/H7 IIV Naïve Subjects

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Principal Investigator: Richard Rupp, MD

For more information click here
NCT03692871: A Study to Evaluate the Safety and Tolerability of V114 and Prevnar 13™ in Healthy Infants (V114-031/PNEU-LINK)

Sponsor: Merck Sharp & Dohme Corp.
Principal Investigator: Marcela Navarro, MD

For more information click here
NCT03682120: A Phase II Study in Healthy Adults 18-64 Years Old to Assess the Safety, Reactogenicity and Immunogenicity of a Seqirus A/H7N9 Inactivated Influenza Vaccine Administered Intramuscularly With or Without MF59(R) Adjuvant

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Principal Investigator: Richard Rupp, MD

For more information click here
NCT03620162: A Study to Evaluate the Interchangeability of V114 and Prevnar 13™ in Healthy Infants (V114-027/PNEU-DIRECTION)

Sponsor: Merck Sharp & Dohme Corp.
Principal Investigator: Richard Rupp, MD

For more information click here
NCT03537508: Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US

Sponsor: Sanofi Pasteur
Principal Investigator: Richard Rupp, MD

For more information click here
NCT03524118: A Double-blind, Randomized, Placebo-controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MK-1654 in Pre-Term and Full-Term Infants

Sponsor: Merck Sharp & Dohme Corp.
Principal Investigator: Richard Rupp, MD
For more information click here
NCT03512288: Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Vaccine in Healthy Infants (B747-1003)

Sponsor: Pfizer Inc.
Principal Investigator: Richard Rupp, MD

For more information click here
NCT03486834: Safety, Tolerability, and Efficacy of the Human Cytomegalovirus Vaccine (V160) in Healthy Women 16 to 35 Years of Age (V160-002)

Sponsor: Merck Sharp & Dohme Corp
Principal Investigator: Richard Rupp, MD

For more information click here
NCT03480763: A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Healthy Adults 50 Years of Age or Older (V114-016/PNEU-PATH)

Sponsor: Merck Sharp & Dohme Corp.
Principal Investigator: Richard Rupp, MD

For more information click here
NCT03090191: A phase III, placebo-controlled, randomized, observer-blinded, study to evaluate efficacy, and tolerability of a Clostridium difficile vaccine in adults 50 years of age and older (CLOVER)

Sponsor: Pfizer Inc.
Principal Investigator: Richard Rupp, MD

For more information click here