Description: Outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens.
Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes.
Vaccinology: An Essential Guide is a perfect tool designed for undergraduates and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.
About the Editors
Drs. Alan Barrett and Gregg Milligan are world-renowned experts in vaccine development and viral immunology. Dr. Barrett, a recognized leader in the biology of flaviviruses, researches tropical virus diseases such as dengue, West Nile, yellow fever and Japanese encephalitis. He has made important contributions to molecular aspects of immunogens and preclinical development of candidate vaccines for these diseases, and studies on the current yellow fever 17D vaccine. Dr. Milligan's research focuses on the innate and adaptive immune responses to herpesviruses. Additionally, he examines the linkage of the innate immune response to vaccines with the development of adaptive immune responses and the role of tissue-resident immune memory cells in protection against virus infections and disease.
Eleven of Tweleve UTMB Contributing Authors
Front Row: Richard Rupp MD, David Walker MD, Bridget Hawkins PhD MBA, Christine Arcari PhD MPH
Back Row: Jai Rudra PhD, Gregg Milligan PhD, Alfredo Torres PhD, Jere McBride PhD, David Bealsey PhD, Nigel Bourne PhD, Alan Barrett PhD
Not pictured: Dennis Trent PhD
The SCVD co-sponsored the National Foundation for Infectious Diseases’ (NFID’s) 15th Annual Conference on Vaccine Research, held in Baltimore, MD on May 7-9, 2012. This meeting attracted 300 participants including SCVD sponsored trainees and faculty. We held an abstract competition for trainees and received many excellent applications from graduate students and postdoctoral scientists. Jingya Xia, a graduate student in Dr. Gregg N Milligan's laboratory, presented her research titled: “Deficiency of TLR3 and MyD88-dependent signalling impairs T and B cell responses to a live attenuated single cycle vaccine”. Dr. Olga Lihoradova, a postdoctoral fellow in Dr. Tetsuro Ikegami's lab, presented her research entitled,“Characterization of Rift Valley fever MP-12 vaccine encodingthe NSs gene derived from other phleboviruses”.
Congrats to Dr. Olga Lihoradova for winning the prestigious Maurice R. Hilleman Early Stage Career Investigator Award at the NFID meeting! The Maurice R. Hilleman Early-Stage Career Investigator Award memorializes the lifetime achievements of Dr. Maurice R. Hilleman in the field of vacinology and provides $10,000 to support research activities at the awardee’s institution as well as a travel stipend and complimentary registration to attend the following year’s Annual Conference on Vaccine Research.
We also staffed an information booth in the exhibition hall, providing an opportunity to inform the attendees about SCVD. Bridget E Hawkins, PhD, MBA, and Richard E Rupp, MD, provided information about vaccine-related research, education and clinical trials being undertaken at the University of Texas Medical Branch (UTMB).
SCVD Travel Award Competition for Keystone Symposium
The SCVD held an abstract competition for trainees to the Keystone Symposium on Molecular and Cellular Biology: Immunological Mechanisms of Vaccination held at the Fairmont Château Laurier Hotel in Ottawa, Ontario, Canada, on December 13-18, 2012.
We received many excellent applications from graduate students and postdoctoral scientists. Christie Hay, a graduate student in Dr. Lynn Soong's laboratory, was awarded a travel award to attend the Keystone Symposium meeting based on her abstract titled “Leishmania Vaccine Development and Protection”. Shivali Gupta, PhD, a postdoctoral scientist in Dr. Nisha Garg's lab, was also awarded a travel award to attend this meeting for her project “Switching of immune mechanisms elicited by a multi-component DNA-prime/MVA-boost vaccine in response to Trypanosoma cruzi infection and Chagas disease in mice”.
Dr. Gregg N. Milligan, Professor in the Department of Pediatrics and Senior Scientist for the Sealy Center for Vaccine Development, received the James and Vicki McCoy Professorship in Vaccinology on May 11, 2012.
Drs. Bridget Hawkins and Richard Rupp won a President’s Cabinet Award for their project entitled: “Public Vaccine Education Campaign: Enhancing Our Community’s Understanding of the Importance of Vaccines and the Diseases They Prevent”. This award funded a two-year project involving public outreach efforts, podcasts, website content, videos and articles geared towards educating the public about vaccine-preventable diseases and why vaccinations are important.