The Tenth Annual McLauglin Symposium
The Changing Landcape of Vaccine Development:
Vaccines for Biothreats and Emerging and Neglected Diseases

Agenda

Tuesday (11/10/09)
7:00-8:00 Continental Breakfast and Registration
8:15-8:30 Welcome and Opening Remarks
    Alan Barrett, Ph.D.
Director, Sealy Center for Vaccine Development, UTMB
    Garland Anderson, M.D.
Executive Vice-President and Provost, and Dean, School of Medicine, UTMB
8:30-9:30 James W. McLaughlin Lecture
  Introduction: Ashok Chopra, Ph.D.
Kathryn Zoon, Ph.D.
"Vaccine Development Efforts for Biothreats and Emerging and Neglected Diseases in the NIAID Division of Intramural Research"
9:30-12:00 Session 1 – Getting Vaccines To Those Who Need Them
(Moderator: David Beasley, Ph.D.)
    Kevin Anderson, Ph.D. – Department of Homeland Security
"Bioterrorism Preparedness: A risk-based approach to prioritizing vaccine research & development efforts"
    David Wood, Ph.D., World Health Organization
"Pandemic influenza vaccines" (title to be confirmed)
10:30-11:00 Break
    Alba Maria Ropero, M.D. – Pan American Health Organization
"Preparing for the influenza pandemic: Lessons learned from the Americas" (title to be confirmed)
    Larry Smith – Vical Inc.
"DNA Vaccines: Rapid Response to Pandemic Outbreaks"
12:00-1:30 Lunch
1:30-5:30 Session 2 – Bacterial Vaccines (Moderator: Mark Estes, Ph.D.)
    David Walker, M.D. – University of Texas Medical Branch
"Vaccines for Rickettsial diseases"
    Greg Bancroft, Ph.D. – London School of Hygiene and Tropical Medicine
"Cell mediated immune responses and vaccines against Burkholderia pseudomallei"
    David Stephens, M.D. – Emory University
"Protecting the Herd: the Effectiveness of Bacterial Polysaccharide-Protein Conjugate Vaccines"
  3:00-3:30 Break
    L. Garry Adams, D.V.M, Ph.D. – Texas A&M University
"Development of Human Brucellosis Vaccine Candidates"
    Johnny Peterson, Ph.D. – University of Texas Medical Branch
"Pathophysiology of Inhalation Anthrax"
Leonard Smith, Ph.D. – United States Army Medical Research Institute for Infectious Diseases
"Botulism and Vaccines for its Prevention"
5:00-5:30 Selected short talks (2 x 15mins each)
(Moderator: Alan Barrett, Ph.D.)
5:30-7:00 Poster Session / Hors d’Oeuvres & Cocktails
Wednesday (11/11/09)
7:00-8:00 Continental Breakfast / Meet the Speakers
8:15-9:15 The Vaccine Lecture
    Introduction: Alan Barrett, Ph.D.
    Greg Poland, M.D. – Mayo Clinic
"Vaccinomics and Personalized Vaccinology"
9:15-10:45 Session 3 – Enhancing the Immune Response
(Moderator: Richard Rupp, M.D.)
    Heather Davis Ph.D. – Pfizer Vaccine Research
"CpG TLR9 agonists as adjuvants for next generation vaccines"
    Karen Haas, Ph.D. – Wake Forest University
"Factors regulating the protective humoral Immune response to Streptococcus pneumoniae"
    Sara Lustigman, Ph.D. – Lindsley F. Kimball Research Institute, New York Blood Center
"Vaccines against onchocerciasis" (title to be confirmed)
  10:45-11:15 Break
11:15-12:45 Session 4 – Vaccines for Developing Countries and Global Threats (Moderator: Gregg Milligan, Ph.D.)
    Thomas Richie, M.D., Ph.D. – Naval Medical Research Center/Walter Reed Army Institute of Research
"Mechanism versus immunogen: approaches to malaria vaccine development"/;
    Maria Bottazzi, Ph.D. – George Washington University
"The Antipoverty Vaccines: Innovation and new tools for the control of soil-transmitted helminth infections best MEB"
    Nisha Garg, Ph.D. – University of Texas Medical Branch
"Current status of vaccine development efforts against Trypanosoma cruzi and Chagas disease"
12:45-2:15 Lunch
2:15-3:15 John LaMontagne Lecture
    Introduction: Martin Myers, M.D.
    Stanley Plotkin, M.D. – Vaxconsult
"Designing the ideal vaccine"
3:15-5:45 Session 5 – Vaccines for Special populations
(Moderator: Christine Turley, M.D.)
    W. Henry Boom, M.D. – Case Western Reserve University
"Immune evasion by M. tuberculosis: a challenge to be overcome by new TB vaccines"
  3:45-4:15 Break
    Sharon Frey, M.D. – St. Louis University
"Smallpox Scourge: current clinical trials and future direction"
    John Shiver, Ph.D. – Merck
"Development of a novel Staphylococcus aureus vaccine based on a conserved protein antigen"
    Mary Estes, Ph.D. – Baylor College of Medicine
"Norovirus Vaccines: Progress and Challenges"
5:45-7:15 Poster Session & Judging / Hors d’Oeuvres & Cocktails
Thursday (11/12/09)
7:00-8:00 Continental Breakfast/ Meet the Speakers
8:15-9:30 Selected short talks (7 x 15 min)
(Moderator: Gregg Milligan, Ph.D.)
9:30-10:00 Break
10:00-12:00 Session 6 – Viral Vaccines and Vaccine Platforms
(Moderator: Nigel Bourne, Ph.D.)
    John Dong, Ph.D. – GenPhar
"The CAdVax as an Effective and Versatile Multivalent Platform Technology against Biodefense Agents"
    Christian Mandl, M.D., Ph.D. – Novartis
"West Nile Virus Vaccine Strategies Based on Capsid Deletion Mutants and Subviral Particles"
    Scott Weaver, Ph.D. – University of Texas Medical Branch
"Novel approaches to alphavirus attenuation"
    Heinz Feldmann, M.D., Ph.D. – National Institute for Allergy and Infectious Diseases
"Marburg and Ebola Viruses: Pre- and Post-Exposure Vaccination"
12:00-12:30 Closing and Presentation of Post Graduate, Post Doctoral and Resident Awards

For further information contact:
Sandra Rivas
Sealy Center for Vaccine Development
University of Texas Medical Branch
Galveston, Texas 77555-0436
Phone: 409-747-8160
Fax: 409-772-6663
Email: smrivas@utmb.edu



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