Pei-Yong Shi, PhD

Dr. Shi’s laboratory integrates both academic and industrial expertise for basic and translational research. Their research focuses on flaviviruses that cause significant human diseases, such as dengue, West Nile, Japanese encephalitis, and Zika viruses. Despite their global public health burden, there is no clinically approved therapy for flavivirus infection. To address this huge unmet medical need, they take a multidisciplinary approach: (i) to study the molecular mechanism of viral replication, and (ii) to translate the knowledge into vaccine/antiviral products. Many of their projects are highly collaborative with both academic and pharmaceutical partners around the world. They also aspire to apply the knowledge achieved from the flavivirus research to drug discovery and vaccine development for other viral pathogens.

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