The research in my laboratory has focused on viral pathogenesis, vaccine
development and on development of animal models to test new vaccine candidates
and antiviral drugs. My main research interest is in understanding the
mechanisms by which emerging RNA viruses cause encephalitis, hemorrhagic fever
or respiratory diseases. Central nervous system (CNS) invasion by RNA viruses is
particularly a complex and fascinating process. We seek to elucidate the nature
of the neuroinflammatory response to CNS invasion by viruses in diverse families
such as Togaviridae, Orthomyxoviridae, Bunyaviridae and Arenaviridae. Our
approach is designed to provide expertise for the development and evaluation of
vaccines and anti-viral drugs in collaboration with partners in academia (within
and between institutions), in biotechnology and in federal agencies.
Search PubMed for Dr. Paessler's publications.