History October 2014:Plans developed to prepare for the possibility of a patient infected with Ebola virus November 2014: ED staff trained on identification, isolation, and care procedures for a patient infected with Ebola virus December 2014:Negative pressure rooms previously identified for care of potential SARS patients rehabilitated for the care of Ebola virus disease patients 2015:Training program developed for Biocontainment Care Unit staff UTMB Biocontainment Care Unit team established March - April 2015:CDC/ASPR designate UTMB to be HHS Region VI Regional Emerging Special Pathogens Treatment Center (RESPTC) 2015-2016:Construction begins on new state of the art Biocontainment Care Unit at UTMB May 2019:UTMB’s 6-bed Biocontainment Care Unit ribbon cutting ceremony March 2020:Biocontainment Care Unit staff develop videos demonstrating proper PPE donning and doffing when treating COVID-19 patients for use across UTMB campuses and for EMS personnel Provided Just in Time Training to clinical staff across all UTMB campuses in the proper use of Personal Air Purifying Respirators (PAPR) for aerosolizing procedure Biorepository for Severe Emerging Infections (BSEI) established, holds nearly 10,000 clinical specimens from over 100 subjects with detailed clinical data March 2020 – June 2021:UTMB participates in the Adaptive COVID-19 Treatment Trial (ACTT), leading to 4 primary publications including data which led to the issuance of EUAs for remdesivir and baricitinib for the treatment of COVID-19 SPECTRE faculty presented several seminars and lead the development of UTMB guidelines regarding treatment of patients with COVID-19 April –August 2020: Department of Biosafety validated and started an N95 filtering facepiece respirator reprocessing program. Over 15,000 N95 respirators were reprocessed during this time. June 2020:UTMB onboards Clinical Characterization Protocol for Severe Emerging Infections (CCPSEI) for collection of biospecimens and clinical data from consented subjects with suspected or confirmed severe emerging infections July 2021:UTMB Department of Biosafety advises on infection control and prevention practices and waste handling for monkeypox case in Dallas, TX at the request of CDC May 2022: NETEC performs Annual Readiness Consultation for UTMB’s Biocontainment Care Unit