Rare Disease Day® is held globally to raise awareness about rare diseases and their impact on patients. The 2025 FDA-NIH Rare Disease Day, sponsored by NCATS and the FDA, will take place on Feb. 27-28 at NIH. The event features discussions, patient stories, exhibits, and scientific posters. It aims to advance research and foster dialogue within the rare disease community. NCATS and FDA support research to address the challenges of rare diseases, with efforts focused on diagnostics, treatments, and regulatory support.