Zbigniew Gugala, MD, PhD

adj_Faculty-GugalaAssociate Professor
Distinguished Teaching Professor
Director of Research


1987-1993, The Jagiellonian University, Cracow, Poland, Medical Doctor (MD)
1991-1993, The Jagiellonian University, Cracow, Poland, Faculty of Philosophy
2003, The University of Groningen, The Netherlands, Doctor of Philosophy (PhD)

Professional and Teaching Experience

1991-1993, The University of Mining and Metallurgy, Crakow, Poland, Faculty of Materials Science and Ceramics
1990, 1992, 1994-1997, AO Research Institute, Davos, Switzerland
1998-2003, Postdoctoral Associate, Department of Orthopaedic Surgery, Baylor College of Medicine, Houston, TX

Select Peer-Reviewed Publications (from a list of 79)

  1. Gugala Z, Gogolewski S. Regeneration of segmental diaphyseal defects in sheep tibiae using resorbable polymeric membranes: a preliminary study. J Orthop Trauma 13(3):187-195, 1999.
  2. Gugala Z., Gogolewski S. In vitro growth and activity of primary chondrocytes on a resorbable polylactide three-dimensional scaffold. J Biomed Mater Res 49(2):183-191, 2000.
  3. Cobos J, Lindsey RW, Gugala Z. The cylindrical titanium mesh cage for the treatment of a long bone defect: description of a new technique and report of two cases. J Orthop Trauma 14(1):54-59, 2000.
  4. Gugala Z, Nana A, Lindsey RW. Tibial intramedullary nail distal interlocking screw placement: a comparison of the free-hand versus distally-based targeting device. Injury 32 (Suppl 4):21-5, 2001.
  5. Olmsted EA, Blum JS, Rill D, Yotnda P, Gugala Z, Lindsey RW, Davis AR. Identification of a novel regulatory mechanism for AdBMP2 expression in human bone marrow stromal Cells. J Cell Biochem 82(1):11-21, 2001.
  6. Olmsted EA, Gugala Z, Gannon FH, Yotnda P, McAlhany R, Lindsey RW, Davis AR. Use of chimeric adenovirus vector enhances BMP-2 production and bone formation. Hum Gene Ther 13(10):1337-1347, 2002.
  7. Gugala Z, Gogolewski S. Healing of critical-size segmental bone defects in the sheep tibiae using bioresorbable polylactide membranes. Injury 33 (Suppl 2):B71-76, 2002.
  8. Gugala Z, Lindsey RW. Classification of gunshot injuries in civilians. Clin Orthop 408:65-81, 2003.
  9. Lavoie S, Lindsey RW, Gugala Z, Kirking B, Hipp JA. Threaded interbody cages for the lumbar fusion: an in vitro study of load sharing and kinematics. Clin Orthop 408:174-179, 2003.
  10. Gugala Z, Olmsted-Davis EA, Gannon FH, Lindsey RW, Davis AR. Osteoinduction by ex vivo adenovirus-mediated BMP2 delivery Is Independent of cell type. Gene Therapy 10(16):1289-1296, 2003.
  11. Olmsted-Davis EA, Gugala Z, Gannon FH, Lindsey RW, Davis AR. Primitive hematopoetic SP cells are precursors of the osteoblasts. Proc Natl Acad Sci USA 100(26):15877-15882, 2003.
  12. Gugala Z, Gogolewski S. Differentiation, growth, and activity of rat bone marrow stromal cells on polylactide membranes with well-defined surface characteristics. Biomaterials 25:2299-2307, 2004.
  13. Gugala Z, Gogolewski S. Protein adsorption, attachment, growth, and activity of primary osteoblasts on polylactide membranes. Biomaterials 25:2341-2351, 2004.
  14. Lindsey RW, Gugala Z. Cylindrical titanium mesh cage for the reconstruction of long bone defects. Osteo Trauma Care 12:108-115, 2004.
  15. Gugala Z, Gogolewski S. The in vitro growth and activity of sheep osteoblasts on three-dimensional scaffolds from poly(L/DL-lactide) 80/20%. J Biomed Mater Res 25(12):2341-2351, 2005.
  16. Gugala Z, Gogolewski S. The in vitro growth and activity of sheep osteoblasts on three-dimensional scaffolds from poly(L/DL-lactide) 80/20%. J Biomed Mater Res A 75(3):702-709, 2005.
  17. Fouletier-Dilling CM, Bosch P, Davis AR, Shafer JA, Stice SL, Gugala Z, Gannon FH, Olmsted-Davis EA. Novel compound enables high-level adenovirus transduction in the absence of an adenovirus-specific receptor. Hum Gene Ther 16(11):1287-1297, 2005.
  18. Gugala Z, Gogolewski S. Attachment, growth, and activity of rat osteoblasts on polylactide membranes treated with various low-temperature radiofrequency plasmas. J Biomed Mater Res A 76(2):288-299, 2006.
  19. Lindsey RW, Gugala Z, Milne E, Sun W, Gannon FH, Latta LL. The efficacy of cylindrical titanium mesh cage for the reconstruction of a critical-size canine segmental femoral diaphyseal defect. J Orthop Res 24(7):1438-1453, 2006.
  20. Gugala Z, Davis AR, Fouletier-Dilling CM, Gannon FH, Lindsey RW, Olmsted-Davis EA. Adenovirus BMP2-induced osteogenesis in combination with collagen carriers. Biomaterials 28(30):4469-4479, 2007.
  21. Gugala Z, Lindsey RW, Gogolewski S. New Approaches in the treatment of critical-size segmental defects in long bones. Macromol Symposia 253(1):147-161, 2007.
  22. Mays M, Lin D, Gugala Z, Lindsey RW. Efficacy of repeat shoulder magnetic resonance imaging. Orthopedics 2008; 31:543-549, 2008.
  23. Lindsey RW, Ahmed S, Overturf S, Tan, Gugala Z. Accuracy of lag screw placement for the dynamic hip screw and the cephalomedullary nail. Orthopedics 32(7):488, 2009.
  24. Anderson PA, Gugala Z, Lindsey RW, Schoenfeld AJ, Harris MB. Clearing the cervical spine in the blunt trauma patient. J Am Acad Orhop Surg 18(3):149-159, 2010.
  25. Gugala Z, Qaisi YT, Hipp JA, Lindsey RW. Long-term Functional implications of the iatrogenic rotational malalignment of healed diaphyseal femur fractures following intramedullary nailing. Clin Biomech 26:274–277, 2011.


  1. Gugala Z. “Resorbable Polymeric Scaffolds for Tissue Repair, Regeneration, and Engineering”. Krakow, Poland: AA Press, 2003. (ISBN 83-919149-0-7)
  2. Lindsey RW, Gugala Z (Eds). Orthopaedic Implants: Application, Complications, and Management. Springer Verlag. To Be Published in 2015.

Book Chapters

  1. Lindsey RW, Gugala Z. Spinal Cord Injury as a Result of Ballistic Trauma. In: “Spine: State of the Art Reviews” Spinal Cord Injuries 13(3). Chapman JR (Ed). Philadelphia: Hanley & Belfus, Inc., 1999, pp. 529-547. (ISBN 1-56053-291-2).
  2. Lindsey RW, Gugala Z. Subtrochanteric Fractures of the Femur. In: “Fracture: Current Diagnosis and Treatment” Moehring HD, Greenspan A (Eds). McGraw Hill, 2000, pp. 107-115. (ISBN 0-0713-5902-8).
  3. Lindsey RW, Pneumaticos SG, Gugala Z. Management Techniques for Spinal Injuries. In: “Skeletal Trauma” Browner B, Jupiter J, Levine A, Trafton P, (Eds). Elsevier Science, 2003, pp. 746-776. (ISBN 0-7216-9175-7).
  4. Lindsey RW, Gugala Z. Gunshot Injuries to the Thoracolumbar Spine. In: “The Management of Thoracolumbar Fractures” Reitman C (Ed). Rosemont, IL: The American Academy of Orthopaedic Surgeons, 2004, pp. 85-96. (ISBN 0-89203-322-3).
  5. Lindsey RW, Gugala Z, Torga-Spak R. The Long-Term Retention versus Removal of Orthopaedic Trauma Fixation Implants. In: “Orthopaedic Knowledge Update: Trauma” 3rd Edition. Tornetta P, Baumgaertner M (Eds). American Academy of Orthopaedic Surgeons, Rosemont 2005, pp.141-148. (ISBN 0-89203-347-9).
  6. Lindsey RW, Gugala Z, Pneumaticos SG. Injuries of the Vertebrae and Spinal Cord. In: “Trauma” 6th Edition E.E. Moore, D.V. Feliciano, K.L. Mattox (Eds). McGraw Hill, 2008, pp.479-511. (ISBN 0-07-146912-5).
  7. Lindsey RW, Gugala Z. Pre-Imaging Cervical Spine Clearance Guidelines in Trauma Patients. In: “The Cervical Spine” Vaccaro AR (Ed). Rothman-Lippincott Williams & Wilkins, Philadelphia. 2009, pp.111-127. (ISBN 0-7817-6702-4).
  8. Lindsey RW, Gugala Z. Clearing the Cervical Spine. In: “Spine Trauma - Surgical Techniques” Patel VV, Burger E, Brown C (Eds). Springer Verlag. Berlin Heidelberg 2010, pp.11-31. (ISBN 978-3-642-03693-4).
  9. Gugala Z, Lindsey RW. Civilian Gunshot Injuries to the Spine. In: “Spine Trauma - Surgical Techniques” Patel VV, Burger E, C. Brown C (Eds) Springer Verlag. Berlin Heidelberg 2010, pp. 377-397. (ISBN 978-3-642-03693-4).
  10. Lindsey RW, Gugala Z. The Management of Type II and III Odontoid Fractures. A Systematic Review. In: “Spine and Spinal Cord Trauma: Evidence-Based Management” Vaccaro AR, Fehlings MG, Dvorak M (Eds). Thieme. New York, Stuttgart 2011, pp. 229-247 (ISBN 978-1-604-06221-2).
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