About Us Biochemistry and Molecular Biology

Two doctors reviewing information on the computer screen

The Department of Biochemistry & Molecular Biology has 20 primary faculty, 4 administrative staff and over 100 students, postdoctoral fellows and scientists. Departmental members seek to understand the molecular basis of health and disease by focusing on a broad range of topics in basic biology, biochemistry and biophysics. Specific areas of interest include protein structural biology, genome biology, and mechanobiology. The Department houses several core facilities allowing for the application of the latest technologies to ongoing research projects. This includes the Next Generation Sequencing Core, Mass Spectrometry Facility, SCSB X-Ray Crystallography Laboratory and Cryo-electron Microscopy Facility all led by Research Faculty in the Department. The Department also benefits from a close relationship with the Sealy Center for Structural Biology and Molecular Biophysics.

The BMB Department is also home to the Biochemistry, Cellular and Molecular Biology Graduate Program, which includes the Biochemistry and Molecular Biology Track and the Structural Biology and Biophysics Track. The Program is designed to prepare students for careers investigating the molecular nature of biomedical phenomena and translating that knowledge to improve human health. Our curriculum provides training in cutting edge technology, critical thinking, and verbal and written communication skills, preparing graduates to be fully competitive for positions in various career paths.

Meet the Faculty

  • Cryo-ET of Toxoplasma gondii

    Professional Photo of Li-av Segev Zarko​
    Li-av Segev Zarko​ ​​, PhD
    Cryo-ET of Toxoplasma gondii

  • Structure of SARS-CoV-2 Nsp13

    Professional Photo of Mark White​
    Mark White​ ​​, PhD
    Structure of SARS-CoV-2 Nsp13​

  • Human iPSC-derived cardiomyocytes​

    Professional Photo of Michelle Ward​
    Michelle Ward​ ​​, PhD
    Human iPSC-derived cardiomyocytes

  • Chemokine-neutrophil axis and infection​

    Professional Photo of Krishna Rajarathnam​
    Krishna Rajarathnam​ ​​, PhD
    Chemokine-neutrophil axis and infection

  • Phage structure & function

    Professional Photo of Petr Leiman
    Petr Leiman ​​, PhD
    Phage structure & function

  • NMR biophysical chemistry

    Professional Photo of Junji Iwahara
    Junji Iwahara​​, PhD
    NMR biophysical chemistry

  • Biomembrane force probe

    Professional Photo of Yunfeng Chen
    Yunfeng Chen​​, PhD
    Biomembrane force probe

  • 3D mosaic protein

    Professional Photo of Werner Braun
    Werner Braun​​, PhD
    3D mosaic protein
    VEEV (pink) with epitope (blue)
    CHIKV (green) with epitope (red)

  • Regulation of protein biosynthesis​

    Professional Photo of Matthieu Gagnon, PhD
    Matthieu Gagnon​​, PhD
    Regulation of protein ​biosynthesis

  • Norovirus shape shifting​: in circulation (left), in the gut (right)

    Professional Photo of Thomas Smith, PhD
    Thomas Smith​, PhDM
    Norovirus shape shifting​: in circulation (left), in the gut (right)

  • Single-genome structure ​and function

    Professional Photo of Guy Nir, PhD
    Guy Nir, PhDM
    Single-genome structure & function

Areas of Research

The BMB Department conducts research in a broad range of topics focused on understanding the molecular basis of health and disease. Research spans from DNA to RNA to proteins to cells and their interactions with the environment. Topics are addressed through a variety of genetic, molecular, structural, cellular, and computational biology approaches and include: